Gene Symbol | BRF2 |
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Entrez Gene | 55290 |
Alt Symbol | BRFU, TFIIIB50 |
Species | Human |
Gene Type | protein-coding |
Description | BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit |
Other Description | B-related factor 2|BRF-2|BRF2, subunit of RNA polymerase III transcription initiation factor, BRF1-like|RNA polymerase III transcription initiation factor BRFU|hBRFU|hTFIIIB50|transcription factor IIB- related factor, TFIIIB50|transcription factor IIIB 50 kDa subunit |
Swissprots | Q9H3B3 D3DSW6 Q9NUY6 Q9HAW0 B4DFZ6 B2RD62 Q9H2Y3 |
Accessions | EAW63351 EAW63352 EAW63353 Q9HAW0 AA496239 AF130058 AAG35486 AF206673 AAG35669 AF298153 AAG30222 AK001914 BAA91975 AK294337 BAG57607 AK315420 BAG37809 BC010648 AAH10648 DA688249 EU446514 ABZ92043 NM_018310 NP_060780 |
Function | General activator of RNA polymerase III transcription. Factor exclusively required for RNA polymerase III transcription of genes with promoter elements upstream of the initiation sites. {ECO:0000269|PubMed:11040218, ECO:0000269|PubMed:11121026, ECO:0000269|PubMed:11564744}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:17505538}. |
BRF2 CRISPR/Cas9 KO Plasmid (h) - sc-409283 from Santa Cruz Biotechnology
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BRF2 HDR Plasmid (h) - sc-409283-HDR from Santa Cruz Biotechnology
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BRF2 Double Nickase Plasmid (h) - sc-409283-NIC from Santa Cruz Biotechnology
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BRF2 Double Nickase Plasmid (h2) - sc-409283-NIC-2 from Santa Cruz Biotechnology
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BRF2 CRISPR Activation Plasmid (h) - sc-409283-ACT from Santa Cruz Biotechnology
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BRF2 CRISPR Activation Plasmid (h2) - sc-409283-ACT-2 from Santa Cruz Biotechnology
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BRF2 Lentiviral Activation Particles (h) - sc-409283-LAC from Santa Cruz Biotechnology
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BRF2 Lentiviral Activation Particles (h2) - sc-409283-LAC-2 from Santa Cruz Biotechnology
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BRF2 siRNA (h) - sc-106763 from Santa Cruz Biotechnology
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BRF2 shRNA Plasmid (h) - sc-106763-SH from Santa Cruz Biotechnology
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BRF2 shRNA (h) Lentiviral Particles - sc-106763-V from Santa Cruz Biotechnology
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BRF2 RNAi - H00055290-R01 from Novus Biologicals
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MISSION® esiRNA - EHU051051 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN4059 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4059 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04377 from Sigma-Aldrich
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BRF2 siRNA (Human) - CRJ0630 from Cohesion Biosciences
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BRF2 - MBS8208311 from MyBioSource
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shRNA set against Human BRF2 (NM_018310.3) - SHH247706 from Creative biogene
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BRF2 shRNA Plasmid (Human) - CHJ0630 from Cohesion Biosciences
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BRF2 miRNA 3'UTR clone - MiUTR3H-08901 from Creative biogene
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