Gene Symbol |
CYTIP
|
Entrez Gene |
9595
|
Alt Symbol |
B3-1, CASP, CYBR, CYTHIP, HE, PSCDBP
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
cytohesin 1 interacting protein
|
Other Description |
cbp HE|cytohesin binder and regulator|cytohesin binding protein HE|cytohesin-1 interacting protein|cytohesin-associated scaffolding protein|cytohesin-binding protein HE|cytohesin-interacting protein|pleckstrin homology Sec7 and coiled-coil domains-binding protein|pleckstrin homology, Sec7 and coiled-coil domains, binding protein|pleckstrin homology, Sec7 and coiled/coil domains, binding protein
|
Swissprots |
O60759 Q8NE32 Q15630 B4DWH9
|
Accessions |
AAY14898 EAX11447 O60759 AF068836 AAC19129 AK301544 BAG63041 AK312753 BAG35620 BC036449 AAH36449 CD642163 DB219691 HQ447813 ADQ32297 L06633 AAA16575 NM_004288 NP_004279
|
Function |
By its binding to cytohesin-1 (CYTH1), it modifies activation of ARFs by CYTH1 and its precise function may be to sequester CYTH1 in the cytoplasm.
|
Subcellular Location |
Cytoplasm. Early endosome. Note=Recruited from the cytosol to endosomes by SNX27.
|
Tissue Specificity |
Expressed in lymph nodes, thymus, spleen, lung, peripheral blood leukocytes and bone marrow. {ECO:0000269|PubMed:11867758, ECO:0000269|PubMed:12606567}.
|