Gene Symbol | IRS2 |
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Entrez Gene | 8660 |
Alt Symbol | IRS-2 |
Species | Human |
Gene Type | protein-coding |
Description | insulin receptor substrate 2 |
Other Description | - |
Swissprots | Q9BZG0 Q96RR2 Q9Y6I5 Q9Y4H2 |
Accessions | AAD55239 AAG50013 AAK66750 AAK66751 AAK83053 BAA24500 BAB84688 CCQ43232 Q9Y4H2 AF073310 AAD21531 AF161416 AAF28976 BC012414 BC026044 BC042858 BC063516 BC066356 BC110638 CA416129 CA952668 NM_003749 NP_003740 |
Function | May mediate the control of various cellular processes by insulin. |
Subcellular Location | Cytoplasm, cytosol {ECO:0000250}. |
Top Pathways | Insulin signaling pathway, Adipocytokine signaling pathway, Type II diabetes mellitus, MicroRNAs in cancer, Non-alcoholic fatty liver disease (NAFLD) |
IRS-2 CRISPR/Cas9 KO Plasmid (h) - sc-400474 from Santa Cruz Biotechnology
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IRS-2 HDR Plasmid (h) - sc-400474-HDR from Santa Cruz Biotechnology
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IRS-2 Double Nickase Plasmid (h) - sc-400474-NIC from Santa Cruz Biotechnology
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IRS-2 Double Nickase Plasmid (h2) - sc-400474-NIC-2 from Santa Cruz Biotechnology
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IRS-2 CRISPR Activation Plasmid (h) - sc-400474-ACT from Santa Cruz Biotechnology
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IRS-2 CRISPR Activation Plasmid (h2) - sc-400474-ACT-2 from Santa Cruz Biotechnology
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IRS-2 Lentiviral Activation Particles (h) - sc-400474-LAC from Santa Cruz Biotechnology
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IRS-2 Lentiviral Activation Particles (h2) - sc-400474-LAC-2 from Santa Cruz Biotechnology
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IRS-2 siRNA (h) - sc-29378 from Santa Cruz Biotechnology
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IRS-2 shRNA Plasmid (h) - sc-29378-SH from Santa Cruz Biotechnology
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IRS-2 shRNA (h) Lentiviral Particles - sc-29378-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN10775 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10775 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR12916 from Sigma-Aldrich
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IRS2 siRNA (Human) - CRH5695 from Cohesion Biosciences
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IRS2 - MBS827791 from MyBioSource
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IRS-2 CRISPR/Cas9 KO Plasmid (h2) - sc-400474-KO-2 from Santa Cruz Biotechnology
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IRS-2 HDR Plasmid (h2) - sc-400474-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human IRS2 (NM_003749.2) - SHH320765 from Creative biogene
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shRNA set against Human IRS2(NM_003749.2) - SHL173766 from Creative biogene
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Human IRS2 siRNA - orb266197 from Biorbyt
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IRS2 shRNA Plasmid (Human) - CHH5695 from Cohesion Biosciences
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IRS2 miRNA 3'UTR clone - MiUTR1H-05000 from Creative biogene
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