Gene Symbol | EGFL7 |
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Entrez Gene | 51162 |
Alt Symbol | NEU1, VE-STATIN, ZNEU1 |
Species | Human |
Gene Type | protein-coding |
Description | EGF-like-domain, multiple 7 |
Other Description | EGF-like protein 7|NOTCH4-like protein|epidermal growth factor-like protein 7|multiple EGF-like domains protein 7|multiple epidermal growth factor-like domains protein 7|vascular endothelial statin |
Swissprots | Q96EG0 Q5M7Y5 B3KRP0 M9VTX9 Q5VUD5 Q9UHF1 |
Accessions | EAW88244 EAW88245 EAW88246 EAW88247 EAW88248 Q9UHF1 AB125649 BAD01469 AF186111 AAF01429 AK091964 BAG52452 AL512735 CAC21666 AY358902 AAQ89261 AY358903 AAQ89262 BC012377 AAH12377 BC088371 AAH88371 BI770335 BM919940 BX361374 BX647866 CB047042 HQ447421 ADQ31907 KC485578 AGJ83826 XM_006717141 XP_006717204 XM_011518764 XP_011517066 XM_011518765 XP_011517067 XM_011518766 XP_011517068 XM_011518767 XP_011517069 XM_011518768 XP_011517070 NM_016215 NP_057299 NM_201446 NP_958854 NR_045110 NR_045111 NR_046367 |
Function | Regulates vascular tubulogenesis in vivo. Inhibits platelet-derived growth factor (PDGF)-BB-induced smooth muscle cell migration and promotes endothelial cell adhesion to the extracellular matrix and angiogenesis. {ECO:0000269|PubMed:23386126, ECO:0000269|PubMed:23639441}. |
Subcellular Location | Secreted, extracellular space {ECO:0000269|PubMed:23386126}. |
EGFL7 CRISPR/Cas9 KO Plasmid (h) - sc-402037 from Santa Cruz Biotechnology
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EGFL7 HDR Plasmid (h) - sc-402037-HDR from Santa Cruz Biotechnology
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EGFL7 Double Nickase Plasmid (h) - sc-402037-NIC from Santa Cruz Biotechnology
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EGFL7 Double Nickase Plasmid (h2) - sc-402037-NIC-2 from Santa Cruz Biotechnology
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EGFL7 CRISPR Activation Plasmid (h) - sc-402037-ACT from Santa Cruz Biotechnology
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EGFL7 CRISPR Activation Plasmid (h2) - sc-402037-ACT-2 from Santa Cruz Biotechnology
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EGFL7 Lentiviral Activation Particles (h) - sc-402037-LAC from Santa Cruz Biotechnology
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EGFL7 Lentiviral Activation Particles (h2) - sc-402037-LAC-2 from Santa Cruz Biotechnology
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EGFL7 siRNA (h) - sc-45471 from Santa Cruz Biotechnology
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EGFL7 shRNA Plasmid (h) - sc-45471-SH from Santa Cruz Biotechnology
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EGFL7 shRNA (h) Lentiviral Particles - sc-45471-V from Santa Cruz Biotechnology
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VE-Statin/EGFL7 RNAi - H00051162-R01 from Novus Biologicals
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VE-Statin/EGFL7 RNAi - H00051162-R02 from Novus Biologicals
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MISSION® esiRNA - EHU071491 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7710 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7710 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02899 from Sigma-Aldrich
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EGFL7 siRNA (Human) - CRH9573 from Cohesion Biosciences
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EGFL7 - MBS8228570 from MyBioSource
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shRNA set against Human EGFL7 (NM_201446.2) - SHH283817 from Creative biogene
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Human EGFL7 siRNA - orb270075 from Biorbyt
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EGFL7 shRNA Plasmid (Human) - CHH9573 from Cohesion Biosciences
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EGFL7 miRNA 3'UTR clone - MiUTR3H-10100 from Creative biogene
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EGFL7 miRNA 3'UTR clone - MiUTR3H-10101 from Creative biogene
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