Gene Symbol | YKT6 |
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Entrez Gene | 10652 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | YKT6 v-SNARE homolog (S. cerevisiae) |
Other Description | R-SNARE|SNARE protein Ykt6|YKT6 v-SNARE protein|YKT6, S. cerevisiae, homolog of|synaptobrevin homolog YKT6 |
Swissprots | Q53F01 O15498 Q6FGU9 Q6IB15 B4DR94 |
Accessions | EAL23763 EAW61111 EAW61112 EAW61113 O15498 AB451317 BAG70131 AB451447 BAG70261 AF091079 AAC72948 AK075018 AK097209 AK223488 BAD97208 AK299158 BAG61206 AK312622 BAG35508 AU130339 BC007319 AAH07319 BT007078 AAP35741 CR456989 CAG33270 CR542008 CAG46805 DQ890653 ABM81579 DQ893833 ABM84759 U95735 AAB81131 XM_005249582 XP_005249639 NM_006555 NP_006546 |
Function | Vesicular soluble NSF attachment protein receptor (v- SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity. {ECO:0000269|PubMed:15215310, ECO:0000269|PubMed:9211930}. |
Subcellular Location | Cytoplasm, cytosol. Cytoplasmic vesicle membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus membrane; Lipid-anchor; Cytoplasmic side. Note=Probably cycles through vesicles between Golgi and endosomes. |
Top Pathways | SNARE interactions in vesicular transport |
v-SNARE Ykt6p CRISPR/Cas9 KO Plasmid (h) - sc-405409 from Santa Cruz Biotechnology
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v-SNARE Ykt6p HDR Plasmid (h) - sc-405409-HDR from Santa Cruz Biotechnology
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v-SNARE Ykt6p Double Nickase Plasmid (h) - sc-405409-NIC from Santa Cruz Biotechnology
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v-SNARE Ykt6p Double Nickase Plasmid (h2) - sc-405409-NIC-2 from Santa Cruz Biotechnology
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v-SNARE Ykt6p CRISPR Activation Plasmid (h) - sc-405409-ACT from Santa Cruz Biotechnology
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v-SNARE Ykt6p CRISPR Activation Plasmid (h2) - sc-405409-ACT-2 from Santa Cruz Biotechnology
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v-SNARE Ykt6p Lentiviral Activation Particles (h) - sc-405409-LAC from Santa Cruz Biotechnology
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v-SNARE Ykt6p Lentiviral Activation Particles (h2) - sc-405409-LAC-2 from Santa Cruz Biotechnology
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v-SNARE Ykt6p siRNA (h) - sc-41342 from Santa Cruz Biotechnology
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v-SNARE Ykt6p shRNA Plasmid (h) - sc-41342-SH from Santa Cruz Biotechnology
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v-SNARE Ykt6p shRNA (h) Lentiviral Particles - sc-41342-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU049611 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN23014 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND23014 from Sigma-Aldrich
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YKT6 siRNA (Human) - CRH7260 from Cohesion Biosciences
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YKT6 - MBS8215445 from MyBioSource
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Human YKT6 siRNA - orb267762 from Biorbyt
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YKT6 shRNA Plasmid (Human) - CHH7260 from Cohesion Biosciences
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