| Gene Symbol |
DAO
|
| Entrez Gene |
102146162
|
| Alt Symbol |
DAAO, DAMOX
|
| Species |
Monkey
|
| Gene Type |
protein-coding
|
| Description |
D-amino-acid oxidase
|
| Other Description |
hypothetical protein
|
| Swissprots |
A2V9Y8
|
| Accessions |
A2V9Y8 AK240621 BAF47375 NM_001283949 NP_001270878 XM_005572162 XP_005572219 XM_005572163 XP_005572220 XM_005572164 XP_005572221
|
| Function |
Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D- amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Peroxisome {ECO:0000250}.
|
| Top Pathways |
Glycine, serine and threonine metabolism, Peroxisome, Arginine and proline metabolism, D-Arginine and D-ornithine metabolism
|