| Gene Symbol | DAO |
|---|---|
| Entrez Gene | 102146162 |
| Alt Symbol | DAAO, DAMOX |
| Species | Monkey |
| Gene Type | protein-coding |
| Description | D-amino-acid oxidase |
| Other Description | hypothetical protein |
| Swissprots | A2V9Y8 |
| Accessions | A2V9Y8 AK240621 BAF47375 NM_001283949 NP_001270878 XM_005572162 XP_005572219 XM_005572163 XP_005572220 XM_005572164 XP_005572221 |
| Function | Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D- amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids (By similarity). {ECO:0000250}. |
| Subcellular Location | Peroxisome {ECO:0000250}. |
| Top Pathways | Glycine, serine and threonine metabolism, Peroxisome, Arginine and proline metabolism, D-Arginine and D-ornithine metabolism |