STAT4

Gene Symbol STAT4
Entrez Gene 6775
Alt Symbol SLEB11
Species Human
Gene Type protein-coding
Description signal transducer and activator of transcription 4
Other Description -
Swissprots Q14765 Q96NZ6
Accessions AAL12164 AAY15055 AAY24184 CAD22977 EAX10846 EAX10847 EAX10848 EAX10849 Q14765 AB209043 BAD92280 AK299976 BAG61799 AK300868 BAG62516 AK301172 BAG62759 BC016694 BC031212 AAH31212 BF966132 DC306142 DC399230 DQ891548 ABM82474 DQ894736 ABM85662 EU304788 ACA01857 EU304789 ACA01858 EU304790 ACA01859 EU304791 ACA01860 EU304792 ACA01861 EU304793 ACA01862 HG495061 L78440 AAB05605 XM_005246817 XP_005246874 XM_006712719 XP_006712782 XM_011511704 XP_011510006 XM_011511705 XP_011510007 XM_011511706 XP_011510008 NM_001243835 NP_001230764 NM_003151 NP_003142
Function Carries out a dual function: signal transduction and activation of transcription. Involved in IL12 signaling.
Subcellular Location Cytoplasm. Nucleus. Note=Translocated into the nucleus in response to phosphorylation.
Top Pathways Jak-STAT signaling pathway, Inflammatory bowel disease (IBD)

Phospho-Stat4 (Tyr693) (D2E4) Rabbit mAb (PE Conjugate) - 13223 from Cell Signaling Technology

Prices $299.00
Sizes 100 µl (50 tests)
Host Rabbit
Clonality Monoclonal
Clone D2E4
Flow cytometric analysis of NK-92 cells, starved of Human Interleukin-2 (hIL-2) #8907 (4 hr) and then either untreated (blue) or IL-12-treated (50 ng/ml, 15 min; green), using Phospho-Stat4 (Tyr693) (D2E4) Rabbit mAb (PE Conjugate).

Phospho-Stat4 (Tyr693) (D2E4) Rabbit mAb - 4134 from Cell Signaling Technology

Prices $287.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D2E4
Western blot analysis of extracts from NK-92 cells, untreated (-) or treated (+) with Human Interleukin-2 (hIL-2) #8907 (10 ng/ml, 15 min) or human interleukin-12 (hIL-12, 50 ng/ml, 15 min), using Phospho-Stat4 (Tyr693) (D2E4) Rabbit mAb (upper) and Stat4 (C46B10) Rabbit mAb #2653 (lower).

Phospho-Stat4 (Tyr693) Antibody - 5267 from Cell Signaling Technology

Prices $287.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from NK-92 cells, untreated or treated with Human Interleukin-2 (hIL-2) #8907 (2ng/ml, 15 minutes), using Phospho-Stat4 (Tyr693) Antibody (upper) or Stat4 (C46B10) Rabbit mAb #2653 (lower).

Stat4 (2A2) Mouse mAb - 5097 from Cell Signaling Technology

Prices $239.00
Sizes 100 µl (10 western blots)
Host Mouse
Clonality Monoclonal
Clone 2A2
Western blot analysis of extracts from COS-7 cells, mock transfected or transfected with human Stat4, using Stat4 (2A2) Mouse mAb.

Stat4 (C46B10) Rabbit mAb - 2653 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone C46B10
Western blot analysis of extracts from various cell lines and from rat thymus using Stat4 (C46B10) Rabbit mAb.

Stat4 (A-12) - sc-365518 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Stat4 (A-12): sc-365518. Western blot analysis of Stat4 expression in Jurkat whole cell lysate.

Stat4 (C-4) - sc-398228 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Stat4 (C-4): sc-398228. Immunofluorescence staining of methanol-fixed NIH/3T3 cells showing cytoplasmic and nuclear localization.

Stat4 (C-18) - sc-33877 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Stat4 (C-20) - sc-486 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Stat4 (C-20): sc-486. Western blot analysis of Stat4 expression in HeLa whole cell lysate (A) and mouse testis extract (B).

Stat4 (H-119) - sc-7959 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Stat4 (H-119): sc-7959. Western blot analysis of Stat4 expression in mouse testis extract.

Stat4 (L-18) - sc-485 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Stat4 (L-18): sc-485. Western blot analysis of Stat4 expression in CTLL-2 (A) and Jurkat (B) whole cell lysates.

Stat4 (N-13) - sc-33876 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Stat4 (PL68) - sc-101160 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
Stat4 (PL68): sc-101160. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human ovary, clear cell carcinoma tissue showing membrane and cytoplasmic localization.

Stat4 (8) - sc-136080 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
Stat4 (8): sc-136080. Western blot analysis of Stat4 expression in rat testis tissue extract.

p-Stat4 (E-2) - sc-28296 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
p-Stat4 (E-2): sc-28296. Immunoperoxidase staining of formalin fixed, paraffin-embedded human testis tissue showing nuclear and cytoplasmic staining of cells in seminiferous ducts and Leydig cells and nuclear staining of smooth muscle cells.

p-Stat4 (Ser 721)-R - sc-22160-R from Santa Cruz Biotechnology

Prices $61.00
Sizes 100 µg/0.5 ml
Host Rabbit
Clonality Polyclonal
p-Stat4 (Ser 721)-R: sc-22160-R. Western blot analysis of Stat4 phosphorylation in 293T whole cell lysate.

p-Stat4 (Tyr 693) - sc-101804 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
p-Stat4 (Tyr 693): sc-101804. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human breast carcinoma tissue showing cytoplamic staining.

p-Stat4 (pY693.38) - sc-136194 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/500 µl
Host Mouse
Clonality Monoclonal
p-Stat4 (pY693.38): sc-136194. Western blot analysis of Stat4 phosphorylation in untreated (A) and pervanadate-treated (B) K-562 whole cell lysates.

Anti-STAT4 (phospho Y693) antibody - ab28815 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab28815, staining human STAT4 in breast carcinoma by immunohistochemistry, paraffin embedded tissue. left: Using STAT4 antibody (ab28815); right: The same antibody preincubated with synthesized phosphopeptide.

Anti-STAT4 (phospho Y693) antibody - ab194732 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-STAT4 (phospho Y693) antibody (ab194732) at 1/500 dilutionLane 1 : HepG2 cell extractLane 2 : HepG2 cell extract treated with IL4

Anti-STAT4 antibody - ab7967 from Abcam

Prices $378.00
Sizes 1 ml
Host Rabbit
Clonality Polyclonal
IHC image of STAT4 staining in human spleen formalin fixed paraffin embedded tissue section, performed on a Leica Bond system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab7967, 5µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

Anti-STAT4 antibody - ab57822 from Abcam

Prices $384.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
STAT4 antibody (ab57822) used in immunofluorescence at 1-5ug/ml on HeLa cells.

Anti-STAT4 antibody - ab31376 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Ab31376, at a dilution of 1/50, staining STAT4 in paraffin embedded breast carcinoma tissue by Immunohistochemistry. Left image: Using Ab31376. Right image: The same antibody preincubated with synthesized peptide.

Anti-STAT4 antibody - ab55357 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using ab55357 at 1/50 dilution. Left: without immunizing peptide; Right: with immunizing peptide

Anti-STAT4 antibody - ab104934 from Abcam

Prices $376.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
Lane 1 : Anti-STAT4 antibody (ab104934) at 1 µg/mlLane 2 : Anti-STAT4 antibody (ab104934) at 1 mg/mlLane 1 : HEK293 lysate overexpressing Human STAT4 in RIPA bufferLane 2 : Mock transfected HEK293 lysateLysates/proteins at 10 µg per lane.
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