Gene Symbol | FECH |
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Entrez Gene | 2235 |
Alt Symbol | EPP, FCE |
Species | Human |
Gene Type | protein-coding |
Description | ferrochelatase |
Other Description | ferrochelatase, mitochondrial|heme synthase|heme synthetase|protoheme ferro-lyase|protoporphyria |
Swissprots | Q8NAN0 A8KA72 P22830 Q8IXN1 |
Accessions | AAA64787 AAM18070 AAM18071 CAA45292 CAB65962 EAW63046 EAW63047 P22830 AI767430 AJ709747 AK092416 BAC03882 AK223190 BAD96910 AK292937 BAF85626 AK299643 BAG61566 BC039841 AAH39841 BG772545 BT019958 AAV38761 BT019959 AAV38762 BU734879 BX571744 CAE11869 D00726 BAA00628 DA990386 XM_011525881 XP_011524183 XM_011525882 XP_011524184 NM_000140 NP_000131 NM_001012515 NP_001012533 |
Function | Catalyzes the ferrous insertion into protoporphyrin IX. |
Subcellular Location | Mitochondrion inner membrane; Peripheral membrane protein; Matrix side. |
Top Pathways | Porphyrin and chlorophyll metabolism |
Ferrochelatase CRISPR/Cas9 KO Plasmid (h) - sc-402043 from Santa Cruz Biotechnology
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Ferrochelatase HDR Plasmid (h) - sc-402043-HDR from Santa Cruz Biotechnology
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Ferrochelatase Double Nickase Plasmid (h) - sc-402043-NIC from Santa Cruz Biotechnology
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Ferrochelatase Double Nickase Plasmid (h2) - sc-402043-NIC-2 from Santa Cruz Biotechnology
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Ferrochelatase CRISPR Activation Plasmid (h) - sc-402043-ACT from Santa Cruz Biotechnology
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Ferrochelatase CRISPR Activation Plasmid (h2) - sc-402043-ACT-2 from Santa Cruz Biotechnology
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Ferrochelatase Lentiviral Activation Particles (h) - sc-402043-LAC from Santa Cruz Biotechnology
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Ferrochelatase Lentiviral Activation Particles (h2) - sc-402043-LAC-2 from Santa Cruz Biotechnology
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Ferrochelatase siRNA (h) - sc-60631 from Santa Cruz Biotechnology
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Ferrochelatase shRNA Plasmid (h) - sc-60631-SH from Santa Cruz Biotechnology
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Ferrochelatase shRNA (h) Lentiviral Particles - sc-60631-V from Santa Cruz Biotechnology
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FECH RNAi - H00002235-R01 from Novus Biologicals
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FECH RNAi - H00002235-R02 from Novus Biologicals
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MISSION® esiRNA - EHU035601 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN8616 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8616 from Sigma-Aldrich
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FECH siRNA (Human) - CRH1558 from Cohesion Biosciences
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FECH - MBS829834 from MyBioSource
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Ferrochelatase CRISPR/Cas9 KO Plasmid (h2) - sc-402043-KO-2 from Santa Cruz Biotechnology
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Ferrochelatase HDR Plasmid (h2) - sc-402043-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human FECH (NM_000140.3) - SHH293989 from Creative biogene
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Human FECH siRNA - orb262060 from Biorbyt
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FECH shRNA Plasmid (Human) - CHH1558 from Cohesion Biosciences
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