Gene Symbol | TAS2R20 |
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Entrez Gene | 259295 |
Alt Symbol | T2R20, T2R49, T2R56, TAS2R49 |
Species | Human |
Gene Type | protein-coding |
Description | taste receptor, type 2, member 20 |
Other Description | taste receptor type 2 member 20|taste receptor type 2 member 49|taste receptor type 2 member 56|taste receptor, type 2, member 49 |
Swissprots | Q496D8 Q2HIZ4 P59549 P59543 Q645X9 |
Accessions | AAM19327 AAM63542 BAD98094 BAD98095 BAD98096 CAI53612 EAW96224 P59543 BC100915 AAI00916 BC100916 AAI00917 BC100917 AAI00918 BC100918 AAI00919 BC113843 AAI13844 BC114451 AAI14452 N24163 NM_176889 NP_795370 |
Function | Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity). {ECO:0000250}. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Tissue Specificity | Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells. |
Top Pathways | Taste transduction |
T2R49 CRISPR/Cas9 KO Plasmid (h) - sc-416780 from Santa Cruz Biotechnology
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T2R49 HDR Plasmid (h) - sc-416780-HDR from Santa Cruz Biotechnology
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T2R49 Double Nickase Plasmid (h) - sc-416780-NIC from Santa Cruz Biotechnology
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T2R49 Double Nickase Plasmid (h2) - sc-416780-NIC-2 from Santa Cruz Biotechnology
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T2R49 CRISPR Activation Plasmid (h) - sc-416780-ACT from Santa Cruz Biotechnology
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T2R49 CRISPR Activation Plasmid (h2) - sc-416780-ACT-2 from Santa Cruz Biotechnology
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T2R49 Lentiviral Activation Particles (h) - sc-416780-LAC from Santa Cruz Biotechnology
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T2R49 Lentiviral Activation Particles (h2) - sc-416780-LAC-2 from Santa Cruz Biotechnology
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T2R49 siRNA (h) - sc-45449 from Santa Cruz Biotechnology
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T2R49 shRNA Plasmid (h) - sc-45449-SH from Santa Cruz Biotechnology
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T2R49 shRNA (h) Lentiviral Particles - sc-45449-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN21018 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21018 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07874 from Sigma-Aldrich
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TAS2R20 siRNA (Human) - CRJ6817 from Cohesion Biosciences
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TAS2R49 RNAi - H00259295-R02 from Novus Biologicals
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TAS2R20 - MBS8221718 from MyBioSource
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shRNA set against Human TAS2R2 (NM_176889.2) - SHH423504 from Creative biogene
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shRNA set against Human TAS2R49(NM_176889.2) - SHL057752 from Creative biogene
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Human TAS2R20 siRNA - orb277318 from Biorbyt
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TAS2R20 shRNA Plasmid (Human) - CHJ6817 from Cohesion Biosciences
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TAS2R20 miRNA 3'UTR clone - MiUTR1H-10205 from Creative biogene
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