Gene Symbol | ATP5I |
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Entrez Gene | 521 |
Alt Symbol | ATP5K |
Species | Human |
Gene Type | protein-coding |
Description | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E |
Other Description | ATP synthase e chain, mitochondrial|ATP synthase subunit e, mitochondrial|ATP synthase, H+ transporting, mitochondrial F0 complex, subunit E|ATPase subunit e|F1F0-ATP synthase, murine e subunit |
Swissprots | P56385 Q0D2L9 |
Accessions | EAW82660 P56385 AB028624 BAA78778 AK000656 BC003679 AAH03679 BC017215 BC105610 AAI05611 BF215596 BG940181 BG943252 BT006922 AAP35568 BT008004 AAP36676 D50371 BAA23322 DA119852 NM_007100 NP_009031 NR_033743 |
Function | Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane. |
Subcellular Location | Mitochondrion. Mitochondrion inner membrane. |
Top Pathways | Oxidative phosphorylation |
ATP5I CRISPR/Cas9 KO Plasmid (h) - sc-410696 from Santa Cruz Biotechnology
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ATP5I HDR Plasmid (h) - sc-410696-HDR from Santa Cruz Biotechnology
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ATP5I Double Nickase Plasmid (h) - sc-410696-NIC from Santa Cruz Biotechnology
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ATP5I Double Nickase Plasmid (h2) - sc-410696-NIC-2 from Santa Cruz Biotechnology
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ATP5I CRISPR Activation Plasmid (h) - sc-410696-ACT from Santa Cruz Biotechnology
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ATP5I CRISPR Activation Plasmid (h2) - sc-410696-ACT-2 from Santa Cruz Biotechnology
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ATP5I Lentiviral Activation Particles (h) - sc-410696-LAC from Santa Cruz Biotechnology
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ATP5I Lentiviral Activation Particles (h2) - sc-410696-LAC-2 from Santa Cruz Biotechnology
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ATP5I siRNA (h) - sc-88980 from Santa Cruz Biotechnology
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ATP5I shRNA Plasmid (h) - sc-88980-SH from Santa Cruz Biotechnology
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ATP5I shRNA (h) Lentiviral Particles - sc-88980-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU101501 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3705 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3705 from Sigma-Aldrich
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ATP5I siRNA (Human) - CRH0360 from Cohesion Biosciences
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ATP5I RNAi - H00000521-R01 from Novus Biologicals
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ATP5I - MBS8225388 from MyBioSource
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shRNA set against Human ATP5I (NM_007100.3) - SHH242854 from Creative biogene
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Human ATP5I siRNA - orb260862 from Biorbyt
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ATP5I shRNA Plasmid (Human) - CHH0360 from Cohesion Biosciences
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ATP5I miRNA 3'UTR clone - MiUTR3H-04179 from Creative biogene
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