Gene Symbol | UBQLN2 |
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Entrez Gene | 29978 |
Alt Symbol | ALS15, CHAP1, DSK2, HRIHFB2157, N4BP4, PLIC2 |
Species | Human |
Gene Type | protein-coding |
Description | ubiquilin 2 |
Other Description | Nedd4 binding protein 4|protein linking IAP with cytoskeleton 2|ubiquilin-2|ubiquitin-like product Chap1/Dsk2 |
Swissprots | Q9UHD9 Q9HAZ4 Q9H3W6 O94798 Q5D027 |
Accessions | EAW93233 Q9UHD9 AB015344 BAA34801 AF189009 AAF17237 AF293385 AAG02474 AK001029 AK297252 BAG59731 AK302885 BAG64063 AL442081 CAC09446 AU310783 BC069237 AAH69237 BI602998 NM_013444 NP_038472 |
Function | Increases the half-life of proteins destined to be degraded by the proteasome; may modulate proteasome-mediated protein degradation. {ECO:0000269|PubMed:10983987}. |
Subcellular Location | Cytoplasm. Nucleus. Note=Where it colocalizes with the proteasome. Associated with fibers in mitotic cells. |
Top Pathways | Protein processing in endoplasmic reticulum |
PLIC-2 CRISPR/Cas9 KO Plasmid (h) - sc-404783 from Santa Cruz Biotechnology
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PLIC-2 HDR Plasmid (h) - sc-404783-HDR from Santa Cruz Biotechnology
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PLIC-2 Double Nickase Plasmid (h) - sc-404783-NIC from Santa Cruz Biotechnology
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PLIC-2 Double Nickase Plasmid (h2) - sc-404783-NIC-2 from Santa Cruz Biotechnology
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PLIC-2 CRISPR Activation Plasmid (h) - sc-404783-ACT from Santa Cruz Biotechnology
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PLIC-2 CRISPR Activation Plasmid (h2) - sc-404783-ACT-2 from Santa Cruz Biotechnology
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PLIC-2 Lentiviral Activation Particles (h) - sc-404783-LAC from Santa Cruz Biotechnology
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PLIC-2 Lentiviral Activation Particles (h2) - sc-404783-LAC-2 from Santa Cruz Biotechnology
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PLIC-2 siRNA (h) - sc-41671 from Santa Cruz Biotechnology
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PLIC-2 shRNA Plasmid (h) - sc-41671-SH from Santa Cruz Biotechnology
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PLIC-2 shRNA (h) Lentiviral Particles - sc-41671-V from Santa Cruz Biotechnology
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Ubiquilin 2 RNAi - H00029978-R01 from Novus Biologicals
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MISSION® esiRNA - EHU029491 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22410 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22410 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR12552 from Sigma-Aldrich
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UBQLN2 siRNA (Human) - CRH9310 from Cohesion Biosciences
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UBQLN2 - MBS8225144 from MyBioSource
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shRNA set against Human UBQLN2 (NM_013444.3) - SHH439468 from Creative biogene
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Human UBQLN2 siRNA - orb269812 from Biorbyt
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UBQLN2 shRNA Plasmid (Human) - CHH9310 from Cohesion Biosciences
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UBQLN2 miRNA 3'UTR clone - MiUTR3H-02678 from Creative biogene
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