Gene Symbol | L3MBTL3 |
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Entrez Gene | 84456 |
Alt Symbol | MBT-1, MBT1 |
Species | Human |
Gene Type | protein-coding |
Description | l(3)mbt-like 3 (Drosophila) |
Other Description | H-l(3)mbt-like protein 3|l(3)mbt-like protein 3|lethal(3)malignant brain tumor-like protein 3 |
Swissprots | Q96JM7 Q4VXE1 Q6P9B5 Q5VUM9 |
Accessions | EAW48073 EAW48074 Q96JM7 AB058701 BAB47427 AI123736 AK092756 AK094137 AK290219 BAF82908 BC060845 AAH60845 CF529850 DA927626 DB059438 EU446541 ABZ92070 HQ257922 ADR82676 XM_005267161 XP_005267218 XM_006715576 XP_006715639 XM_006715578 XP_006715641 XM_011536179 XP_011534481 XM_011536180 XP_011534482 XM_011536181 XP_011534483 XM_011536182 XP_011534484 XM_011536183 XP_011534485 XM_011536184 XP_011534486 NM_001007102 NP_001007103 NM_032438 NP_115814 |
Function | Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Required for normal maturation of myeloid progenitor cells (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000250}. |
L3MBTL3 CRISPR/Cas9 KO Plasmid (h) - sc-413649 from Santa Cruz Biotechnology
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L3MBTL3 HDR Plasmid (h) - sc-413649-HDR from Santa Cruz Biotechnology
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L3MBTL3 Double Nickase Plasmid (h) - sc-413649-NIC from Santa Cruz Biotechnology
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L3MBTL3 Double Nickase Plasmid (h2) - sc-413649-NIC-2 from Santa Cruz Biotechnology
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L3MBTL3 CRISPR Activation Plasmid (h) - sc-413649-ACT from Santa Cruz Biotechnology
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L3MBTL3 CRISPR Activation Plasmid (h2) - sc-413649-ACT-2 from Santa Cruz Biotechnology
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L3MBTL3 Lentiviral Activation Particles (h) - sc-413649-LAC from Santa Cruz Biotechnology
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L3MBTL3 Lentiviral Activation Particles (h2) - sc-413649-LAC-2 from Santa Cruz Biotechnology
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L3MBTL3 siRNA (h) - sc-95210 from Santa Cruz Biotechnology
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L3MBTL3 shRNA Plasmid (h) - sc-95210-SH from Santa Cruz Biotechnology
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L3MBTL3 shRNA (h) Lentiviral Particles - sc-95210-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU126271 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN11514 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11514 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR10276 from Sigma-Aldrich
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L3MBTL3 siRNA (Human) - CRJ3485 from Cohesion Biosciences
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shRNA set against Human L3MBTL3 (NM_001007102.2) - SHH328059 from Creative biogene
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L3MBTL3 shRNA Plasmid (Human) - CHJ3485 from Cohesion Biosciences
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L3MBTL3 miRNA 3'UTR clone - MiUTR3H-15284 from Creative biogene
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L3MBTL3 miRNA 3'UTR clone - MiUTR3H-15285 from Creative biogene
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