Gene Symbol |
CD3E
|
Entrez Gene |
916
|
Alt Symbol |
IMD18, T3E, TCRE
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
CD3e molecule, epsilon (CD3-TCR complex)
|
Other Description |
CD3-epsilon|CD3e antigen, epsilon polypeptide (TiT3 complex)|T-cell antigen receptor complex, epsilon subunit of T3|T-cell surface antigen T3/Leu-4 epsilon chain|T-cell surface glycoprotein CD3 epsilon chain
|
Swissprots |
A8K997 P07766
|
Accessions |
AAA52295 AAA61062 BAJ16130 EAW67360 EAW67361 EAW67362 EAW67363 EAW67364 P07766 AK292612 BAF85301 AK301255 BAG62822 AK311641 BC049847 AAH49847 BI910359 BP366535 X03884 CAA27516 NM_000733 NP_000724
|
Function |
The CD3 complex mediates signal transduction.
|
Subcellular Location |
Membrane; Single-pass type I membrane protein.
|
Top Pathways |
Hematopoietic cell lineage, T cell receptor signaling pathway, Primary immunodeficiency, Chagas disease (American trypanosomiasis), HTLV-I infection
|