Gene Symbol | CD3E |
---|---|
Entrez Gene | 916 |
Alt Symbol | IMD18, T3E, TCRE |
Species | Human |
Gene Type | protein-coding |
Description | CD3e molecule, epsilon (CD3-TCR complex) |
Other Description | CD3-epsilon|CD3e antigen, epsilon polypeptide (TiT3 complex)|T-cell antigen receptor complex, epsilon subunit of T3|T-cell surface antigen T3/Leu-4 epsilon chain|T-cell surface glycoprotein CD3 epsilon chain |
Swissprots | A8K997 P07766 |
Accessions | AAA52295 AAA61062 BAJ16130 EAW67360 EAW67361 EAW67362 EAW67363 EAW67364 P07766 AK292612 BAF85301 AK301255 BAG62822 AK311641 BC049847 AAH49847 BI910359 BP366535 X03884 CAA27516 NM_000733 NP_000724 |
Function | The CD3 complex mediates signal transduction. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Top Pathways | Hematopoietic cell lineage, T cell receptor signaling pathway, Primary immunodeficiency, Chagas disease (American trypanosomiasis), HTLV-I infection |