Gene Symbol | SFSWAP |
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Entrez Gene | 6433 |
Alt Symbol | SFRS8, SWAP |
Species | Human |
Gene Type | protein-coding |
Description | splicing factor, suppressor of white-apricot family |
Other Description | splicing factor, arginine/serine-rich 8 (suppressor-of-white-apricot homolog, Drosophila)|splicing factor, arginine/serine-rich 8 (suppressor-of-white-apricot, Drosophila homolog)|splicing factor, suppressor of white-apricot homolog|suppressor of white apricot protein homolog |
Swissprots | Q6PJF7 F5H6B8 B7ZM97 B2RN45 Q12872 |
Accessions | EAW98526 EAW98527 Q12872 AA410512 AB208921 BAD92158 AK295149 BAG58166 AK310836 BC008707 AAH08707 BC015953 AAH15953 BC024041 AAH24041 BC113420 BC136678 AAI36679 BC142980 AAI42981 BC144364 AAI44365 BM454299 DB468124 U08377 AAA19604 XM_011538653 XP_011536955 XM_011538654 XP_011536956 XM_011538655 XP_011536957 NM_001261411 NP_001248340 NM_004592 NP_004583 NM_152235 |
Function | Plays a role as an alternative splicing regulator. Regulate its own expression at the level of RNA processing. Also regulates the splicing of fibronectin and CD45 genes. May act, at least in part, by interaction with other R/S-containing splicing factors. Represses the splicing of MAPT/Tau exon 10. {ECO:0000269|PubMed:8940107}. |
Subcellular Location | Nucleus {ECO:0000305}. |
SWAP CRISPR/Cas9 KO Plasmid (h) - sc-411003 from Santa Cruz Biotechnology
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SWAP HDR Plasmid (h) - sc-411003-HDR from Santa Cruz Biotechnology
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SWAP Double Nickase Plasmid (h) - sc-411003-NIC from Santa Cruz Biotechnology
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SWAP Double Nickase Plasmid (h2) - sc-411003-NIC-2 from Santa Cruz Biotechnology
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SWAP CRISPR Activation Plasmid (h) - sc-411003-ACT from Santa Cruz Biotechnology
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SWAP CRISPR Activation Plasmid (h2) - sc-411003-ACT-2 from Santa Cruz Biotechnology
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SWAP Lentiviral Activation Particles (h) - sc-411003-LAC from Santa Cruz Biotechnology
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SWAP Lentiviral Activation Particles (h2) - sc-411003-LAC-2 from Santa Cruz Biotechnology
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SFRS8 siRNA (h) - sc-95838 from Santa Cruz Biotechnology
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SFRS8 shRNA Plasmid (h) - sc-95838-SH from Santa Cruz Biotechnology
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SFRS8 shRNA (h) Lentiviral Particles - sc-95838-V from Santa Cruz Biotechnology
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SFRS8 RNAi - H00006433-R01 from Novus Biologicals
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SFRS8 RNAi - H00006433-R02 from Novus Biologicals
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MISSION® esiRNA - EHU041411 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19201 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19201 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01433 from Sigma-Aldrich
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SFSWAP siRNA (Human) - CRH4348 from Cohesion Biosciences
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SFSWAP - MBS8234469 from MyBioSource
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shRNA set against Human SFSWAP (NM_004592.3) - SHH405996 from Creative biogene
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SFSWAP shRNA Plasmid (Human) - CHH4348 from Cohesion Biosciences
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SFSWAP miRNA 3'UTR clone - MiUTR3H-04523 from Creative biogene
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