Gene Symbol | RASD1 |
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Entrez Gene | 51655 |
Alt Symbol | AGS1, DEXRAS1, MGC:26290 |
Species | Human |
Gene Type | protein-coding |
Description | RAS, dexamethasone-induced 1 |
Other Description | activator of G-protein signaling 1|dexamethasone-induced Ras-related protein 1|ras-related protein |
Swissprots | B4DFF4 Q9Y272 B2R709 Q9NYB4 |
Accessions | AAF72997 AAG44256 EAW55705 Q9Y272 AF069506 AAD34206 AF153192 AAD34621 AF172846 AAF01364 AF177335 AAG17979 AF498923 AAM21071 AK294073 BAG57415 AK312796 BAG35656 AM392981 CAL37859 AM393158 CAL38036 AM393716 CAL38592 BC018041 AAH18041 BC042688 NM_001199989 NP_001186918 NM_016084 NP_057168 |
Function | Small GTPase. Negatively regulates the transcription regulation activity of the APBB1/FE65-APP complex via its interaction with APBB1/FE65 (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Cytoplasm, perinuclear region {ECO:0000250}. Nucleus {ECO:0000250}. |
Tissue Specificity | Expressed in a variety of tissues including heart, cardiovascular tissues, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, gastrointestinal and reproductive tissues. {ECO:0000269|PubMed:10673050, ECO:0000269|PubMed:12818426}. |
Top Pathways | Circadian entrainment |
Dexras1 CRISPR/Cas9 KO Plasmid (h) - sc-412234 from Santa Cruz Biotechnology
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Dexras1 HDR Plasmid (h) - sc-412234-HDR from Santa Cruz Biotechnology
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Dexras1 Double Nickase Plasmid (h) - sc-412234-NIC from Santa Cruz Biotechnology
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Dexras1 Double Nickase Plasmid (h2) - sc-412234-NIC-2 from Santa Cruz Biotechnology
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Dexras1 CRISPR Activation Plasmid (h) - sc-412234-ACT from Santa Cruz Biotechnology
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Dexras1 CRISPR Activation Plasmid (h2) - sc-412234-ACT-2 from Santa Cruz Biotechnology
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Dexras1 Lentiviral Activation Particles (h) - sc-412234-LAC from Santa Cruz Biotechnology
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Dexras1 Lentiviral Activation Particles (h2) - sc-412234-LAC-2 from Santa Cruz Biotechnology
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Dexras1 siRNA (h) - sc-41850 from Santa Cruz Biotechnology
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Dexras1 shRNA Plasmid (h) - sc-41850-SH from Santa Cruz Biotechnology
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Dexras1 shRNA (h) Lentiviral Particles - sc-41850-V from Santa Cruz Biotechnology
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Dexras1 RNAi - H00051655-R01 from Novus Biologicals
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MISSION® esiRNA - EHU012561 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17976 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17976 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06276 from Sigma-Aldrich
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RASD1 siRNA (Human) - CRH9884 from Cohesion Biosciences
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RASD1 - MBS8215849 from MyBioSource
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shRNA set against Human RASD1 (NM_016084.4) - SHH389932 from Creative biogene
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Human RASD1 siRNA - orb270386 from Biorbyt
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RASD1 shRNA Plasmid (Human) - CHH9884 from Cohesion Biosciences
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RASD1 miRNA 3'UTR clone - MiUTR3H-07784 from Creative biogene
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