Gene Symbol | CD34 |
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Entrez Gene | 947 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | CD34 molecule |
Other Description | CD34 antigen|hematopoietic progenitor cell antigen CD34 |
Swissprots | Q15971 Q5JTA3 Q9UJB1 Q15970 Q5JTA4 A8K664 P28906 |
Accessions | AAA03659 BAE46748 CAJ01226 EAW93458 EAW93459 P28906 AA022917 AF202879 AAF14634 AF523361 AAM82157 AF538601 AAN15135 AK091890 AK291529 BAF84218 AK293030 BAF85719 AK294381 BAG57638 AK300835 BAG62486 BC039146 AAH39146 BX538076 CAD98000 BX640941 DQ891428 ABM82354 DQ894603 ABM85529 M81104 AAA03181 S53910 AAB25222 S53911 AAB25223 XM_011510170 XP_011508472 NM_001025109 NP_001020280 NM_001773 NP_001764 |
Function | Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Tissue Specificity | Selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues. |
Top Pathways | Hematopoietic cell lineage, Cell adhesion molecules (CAMs) |
CD34 (ICO115) Mouse mAb - 3569 from Cell Signaling Technology
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CD34 (C-18) - sc-7045 from Santa Cruz Biotechnology
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CD34 (H-140) - sc-9095 from Santa Cruz Biotechnology
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CD34 (TUK3) - sc-19587 from Santa Cruz Biotechnology
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CD34 (BI-3C5) - sc-19621 from Santa Cruz Biotechnology
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CD34 (ICO115) - sc-7324 from Santa Cruz Biotechnology
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CD34 (B-6) - sc-74499 from Santa Cruz Biotechnology
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CD34 (D-6) - sc-133082 from Santa Cruz Biotechnology
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CD34 (QBEnd/10) - sc-52312 from Santa Cruz Biotechnology
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CD34 (43A1) - sc-65261 from Santa Cruz Biotechnology
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Anti-CD34 antibody - ab185732 from Abcam
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Anti-CD34 antibody - ab170235 from Abcam
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Anti-CD34 antibody - ab140886 from Abcam
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Anti-CD34 antibody [4H11], prediluted (Alexa Fluor® 488) - ab187568 from Abcam
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Anti-CD34 antibody [4H11], prediluted (Allophycocyanin) - ab155377 from Abcam
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Anti-CD34 antibody [4H11], prediluted (PE/Cy7 ®) - ab155358 from Abcam
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Anti-CD34 antibody [4H11(APG)] - ab762 from Abcam
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Anti-CD34 antibody [4H11[APG]] (Biotin) - ab21893 from Abcam
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Anti-CD34 antibody [4H11[APG]] (FITC) - ab18227 from Abcam
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Anti-CD34 antibody [4H11(APG)], prediluted (Allophycocyanin) - ab18225 from Abcam
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Anti-CD34 antibody [4H11(APG)], prediluted (Phycoerythrin) - ab18228 from Abcam
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Anti-CD34 antibody [581] (FITC) - ab131589 from Abcam
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Anti-CD34 antibody [581] (PE/Cy5®) - ab157304 from Abcam
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Anti-CD34 antibody [581] (PerCP) - ab119840 from Abcam
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Anti-CD34 antibody [581], prediluted (PerCP/Cy5.5®) - ab157325 from Abcam
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