Gene Symbol | KCP |
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Entrez Gene | 375616 |
Alt Symbol | CRIM2, KCP1, NET67 |
Species | Human |
Gene Type | protein-coding |
Description | kielin/chordin-like protein |
Other Description | CRIM-2|KCP-1|cysteine rich BMP regulator 2 (chordin-like)|cysteine-rich BMP regulator 2|cysteine-rich motor neuron 2 protein|kielin|kielin/chordin-like protein 1 |
Swissprots | Q8NBE0 Q6ZWJ8 |
Accessions | EAW83694 Q6ZWJ8 AK090684 BAC03505 AK090715 AK095464 BAC04553 AK122706 BAC85504 XM_011516171 XP_011514473 XM_011516172 XP_011514474 XM_011516173 XP_011514475 XM_011516174 XP_011514476 XM_011516175 XP_011514477 XM_011516176 XP_011514478 XM_011516177 XP_011514479 XM_011516178 XP_011514480 XM_011516179 XP_011514481 XM_011516180 XP_011514482 XM_011516181 XP_011514483 XM_011516182 XP_011514484 XM_011516183 XP_011514485 XM_011516184 XP_011514486 NM_001135914 NP_001129386 NM_199349 NP_955381 |
Function | Enhances bone morphogenetic protein (BMP) signaling in a paracrine manner. In contrast, it inhibits both the activin-A and TGFB1-mediated signaling pathways (By similarity). {ECO:0000250}. |
Subcellular Location | Secreted {ECO:0000250}. |
CRIM2 CRISPR/Cas9 KO Plasmid (h) - sc-415718 from Santa Cruz Biotechnology
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CRIM2 HDR Plasmid (h) - sc-415718-HDR from Santa Cruz Biotechnology
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CRIM2 Double Nickase Plasmid (h) - sc-415718-NIC from Santa Cruz Biotechnology
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CRIM2 Double Nickase Plasmid (h2) - sc-415718-NIC-2 from Santa Cruz Biotechnology
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CRIM2 CRISPR Activation Plasmid (h) - sc-415718-ACT from Santa Cruz Biotechnology
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CRIM2 CRISPR Activation Plasmid (h2) - sc-415718-ACT-2 from Santa Cruz Biotechnology
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CRIM2 Lentiviral Activation Particles (h) - sc-415718-LAC from Santa Cruz Biotechnology
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CRIM2 Lentiviral Activation Particles (h2) - sc-415718-LAC-2 from Santa Cruz Biotechnology
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CRIM2 siRNA (h) - sc-89514 from Santa Cruz Biotechnology
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CRIM2 shRNA Plasmid (h) - sc-89514-SH from Santa Cruz Biotechnology
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CRIM2 shRNA (h) Lentiviral Particles - sc-89514-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU001121 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10998 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10998 from Sigma-Aldrich
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KCP siRNA (Human) - CRJ7678 from Cohesion Biosciences
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shRNA set against Human KCP (NM_001135914.1) - SHH323807 from Creative biogene
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KCP shRNA Plasmid (Human) - CHJ7678 from Cohesion Biosciences
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KCP miRNA 3'UTR clone - MiUTR4H-TG04735 from Creative biogene
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