Gene Symbol | DMRT3 |
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Entrez Gene | 58524 |
Alt Symbol | DMRTA3 |
Species | Human |
Gene Type | protein-coding |
Description | doublesex and mab-3 related transcription factor 3 |
Other Description | DMRT-like family A3|doublesex- and mab-3-related transcription factor 3|testis-specific protein |
Swissprots | Q96SC7 Q7LCH8 Q9NRQ9 Q7LA03 Q9NQL9 |
Accessions | AAF78891 EAW58819 Q9NQL9 AF193873 AAF78892 AF217741 AAF72594 AI052121 AJ301581 CAC37947 BC113584 AAI13585 BC117245 AAI17246 XM_011517997 XP_011516299 NM_021240 NP_067063 |
Function | Probable transcription factor that plays a role in configuring the spinal circuits controlling stride in vertebrates. Involved in neuronal specification within specific subdivision of spinal cord neurons and in the development of a coordinated locomotor network controlling limb movements. May regulate transcription during sexual development (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00070}. |
Tissue Specificity | Expressed in testis. {ECO:0000269|PubMed:10729223}. |
DMRT3 CRISPR/Cas9 KO Plasmid (h) - sc-407329 from Santa Cruz Biotechnology
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DMRT3 HDR Plasmid (h) - sc-407329-HDR from Santa Cruz Biotechnology
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DMRT3 Double Nickase Plasmid (h) - sc-407329-NIC from Santa Cruz Biotechnology
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DMRT3 Double Nickase Plasmid (h2) - sc-407329-NIC-2 from Santa Cruz Biotechnology
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DMRT3 CRISPR Activation Plasmid (h) - sc-407329-ACT from Santa Cruz Biotechnology
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DMRT3 CRISPR Activation Plasmid (h2) - sc-407329-ACT-2 from Santa Cruz Biotechnology
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DMRT3 Lentiviral Activation Particles (h) - sc-407329-LAC from Santa Cruz Biotechnology
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DMRT3 Lentiviral Activation Particles (h2) - sc-407329-LAC-2 from Santa Cruz Biotechnology
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DMRT3 siRNA (h) - sc-77159 from Santa Cruz Biotechnology
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DMRT3 shRNA Plasmid (h) - sc-77159-SH from Santa Cruz Biotechnology
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DMRT3 shRNA (h) Lentiviral Particles - sc-77159-V from Santa Cruz Biotechnology
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DMRT3 RNAi - H00058524-R01 from Novus Biologicals
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MISSION® esiRNA - EHU002281 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7315 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7315 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06157 from Sigma-Aldrich
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DMRT3 siRNA (Human) - CRJ1744 from Cohesion Biosciences
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DMRT3 - MBS8208302 from MyBioSource
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shRNA set against Human DMRT3 (NM_021240.2) - SHH278881 from Creative biogene
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DMRT3 shRNA Plasmid (Human) - CHJ1744 from Cohesion Biosciences
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DMRT3 miRNA 3'UTR clone - MiUTR1H-02890 from Creative biogene
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