Gene Symbol | IL24 |
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Entrez Gene | 11009 |
Alt Symbol | C49A, FISP, IL10B, MDA7, MOB5, ST16 |
Species | Human |
Gene Type | protein-coding |
Description | interleukin 24 |
Other Description | IL-4-induced secreted protein|interleukin-24|melanocyte-associated Mda-7|melanoma differentiation-associated gene 7 protein|suppression of tumorigenicity 16 (melanoma differentiation) |
Swissprots | Q5YLN8 Q96DB0 Q2YHE5 Q96KG4 Q13007 Q53XZ7 |
Accessions | AAG41401 AAK52589 AAL34146 CAJ18816 CAJ98561 CAY39296 CAY86021 EAW93518 EAW93519 Q13007 AI521306 AW949784 AY237723 AAO67513 AY641440 AAV52800 AY641441 AAV52801 BC009681 AAH09681 BP222545 BP222651 BT007156 AAP35820 DQ890656 ABM81582 DQ890657 ABM81583 DQ893836 ABM84762 DQ893843 ABM84769 U16261 AAA91780 XM_011509101 XP_011507403 NM_001185156 NP_001172085 NM_001185157 NP_001172086 NM_001185158 NP_001172087 NM_006850 NP_006841 NM_181339 |
Function | Has antiproliferative properties on melanoma cells and may contribute to terminal cell differentiation. |
Subcellular Location | Secreted {ECO:0000305}. |
Tissue Specificity | Up-regulated in melanoma cells induced to terminally differentiate. |
Top Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway |
MDA-7 CRISPR/Cas9 KO Plasmid (h) - sc-417082 from Santa Cruz Biotechnology
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MDA-7 HDR Plasmid (h) - sc-417082-HDR from Santa Cruz Biotechnology
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MDA-7 Double Nickase Plasmid (h) - sc-417082-NIC from Santa Cruz Biotechnology
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MDA-7 Double Nickase Plasmid (h2) - sc-417082-NIC-2 from Santa Cruz Biotechnology
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MDA-7 CRISPR Activation Plasmid (h) - sc-417082-ACT from Santa Cruz Biotechnology
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MDA-7 CRISPR Activation Plasmid (h2) - sc-417082-ACT-2 from Santa Cruz Biotechnology
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MDA-7 Lentiviral Activation Particles (h) - sc-417082-LAC from Santa Cruz Biotechnology
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MDA-7 Lentiviral Activation Particles (h2) - sc-417082-LAC-2 from Santa Cruz Biotechnology
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MDA-7 siRNA (h) - sc-37446 from Santa Cruz Biotechnology
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MDA-7 shRNA Plasmid (h) - sc-37446-SH from Santa Cruz Biotechnology
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MDA-7 shRNA (h) Lentiviral Particles - sc-37446-V from Santa Cruz Biotechnology
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IL-24 RNAi - H00011009-R02 from Novus Biologicals
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MISSION® esiRNA - EHU077581 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10614 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10614 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR08205 from Sigma-Aldrich
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IL24 siRNA (Human) - CRH7518 from Cohesion Biosciences
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IL-24 RNAi - H00011009-R01 from Novus Biologicals
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IL24 - MBS8200419 from MyBioSource
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shRNA set against Human IL24 (NM_006850.3) - SHH318773 from Creative biogene
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IL24 shRNA Plasmid (Human) - CHH7518 from Cohesion Biosciences
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IL24 miRNA 3'UTR clone - MiUTR4H-TG04502 from Creative biogene
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