| Gene Symbol |
MS4A3
|
| Entrez Gene |
932
|
| Alt Symbol |
CD20L, HTM4
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
|
| Other Description |
CD20 antigen homolog|CD20 antigen-like protein|IgE receptor beta chain|IgE receptor beta subunit|hematopoietic cell 4 transmembrane protein|hematopoietic-specific transmembrane protein 4|membrane-spanning 4-domains subfamily A member 3
|
| Swissprots |
A8MTP8 Q8NHW2 Q96HJ5
|
| Accessions |
AAP14648 EAW73863 EAW73864 Q96HJ5 AL601630 AY095480 AAM23312 BC008487 AAH08487 BE564041 BF210971 BG495577 HQ447086 ADQ31573 L35848 AAA62319 XM_011545363 XP_011543665 NM_001031666 NP_001026836 NM_001031809 NP_001026979 NM_006138 NP_006129
|
| Function |
Hematopoietic modulator for the G1-S cell cycle transition. Modulates the level of phosphorylation of cyclin- dependent kinase 2 (CDK2) through its direct binding to cyclin- dependent kinase inhibitor 3 (CDKN3/KAP). {ECO:0000269|PubMed:11781350}.
|
| Subcellular Location |
Endomembrane system {ECO:0000250}; Multi- pass membrane protein {ECO:0000250}. Cytoplasm, perinuclear region {ECO:0000250}. Note=Located in the perinuclear area.
|
| Tissue Specificity |
Expressed specifically in hematopoietic cells and tissues.
|
![Western Blot: MS4A3 Overexpression Lysate (Adult Normal) [NBL1-13316] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for MS4A3.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/9510_MS4A3%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-13316-img0002.jpg)