Gene Symbol | Rfng |
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Entrez Gene | 19719 |
Alt Symbol | - |
Species | Mouse |
Gene Type | protein-coding |
Description | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
Other Description | O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase|beta-1,3-N-acetylglucosaminyltransferase radical fringe|radical fringe gene homolog |
Swissprots | O09009 B1ATU3 |
Accessions | EDL34802 EDL34803 O09009 AF015770 AAB71670 AK004573 AK178490 AK181501 AK181574 AK181624 AK183109 AK184545 AK187511 AK189194 AK207192 AK212815 AK213809 AK214316 AK217572 AK218494 BC066023 AAH66023 U94350 AAC53261 XM_006532606 XP_006532669 XR_388377 XR_388378 XR_388379 NM_009053 NP_033079 |
Function | Glycosyltransferase that initiates the elongation of O- linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. May be involved in limb formation and in neurogenesis (By similarity). {ECO:0000250}. |
Subcellular Location | Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. |
Tissue Specificity | Detected in all the examined tissues (12.5 dpc). High expression found in adult brain. |
Top Pathways | Other types of O-glycan biosynthesis, Notch signaling pathway |
Radical Fringe CRISPR/Cas9 KO Plasmid (m) - sc-422659 from Santa Cruz Biotechnology
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Radical Fringe HDR Plasmid (m) - sc-422659-HDR from Santa Cruz Biotechnology
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Radical Fringe Double Nickase Plasmid (m) - sc-422659-NIC from Santa Cruz Biotechnology
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Radical Fringe Double Nickase Plasmid (m2) - sc-422659-NIC-2 from Santa Cruz Biotechnology
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Radical Fringe CRISPR Activation Plasmid (m) - sc-422659-ACT from Santa Cruz Biotechnology
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Radical Fringe CRISPR Activation Plasmid (m2) - sc-422659-ACT-2 from Santa Cruz Biotechnology
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Radical Fringe Lentiviral Activation Particles (m) - sc-422659-LAC from Santa Cruz Biotechnology
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Radical Fringe Lentiviral Activation Particles (m2) - sc-422659-LAC-2 from Santa Cruz Biotechnology
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Radical Fringe siRNA (m) - sc-39495 from Santa Cruz Biotechnology
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Radical Fringe shRNA Plasmid (m) - sc-39495-SH from Santa Cruz Biotechnology
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Radical Fringe shRNA (m) Lentiviral Particles - sc-39495-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU055501 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN40113 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND40113 from Sigma-Aldrich
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RFNG siRNA (Mouse) - CRM3466 from Cohesion Biosciences
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RFNG - MBS8202530 from MyBioSource
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shRNA set against Mouse RFNG (NM_009053.2) - SHH392280 from Creative biogene
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shRNA set against Mouse Rfng(NM_009053.2) - SHR177414 from Creative biogene
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Mouse RFNG siRNA - orb282942 from Biorbyt
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RFNG shRNA Plasmid (Mouse) - CHM3466 from Cohesion Biosciences
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RFNG miRNA 3'UTR clone - MiUTR1M-10044 from Creative biogene
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