Gene Symbol | COL1A1 |
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Entrez Gene | 1277 |
Alt Symbol | EDSC, OI1, OI2, OI3, OI4 |
Species | Human |
Gene Type | protein-coding |
Description | collagen, type I, alpha 1 |
Other Description | alpha-1 type I collagen|collagen alpha 1 chain type I|collagen alpha-1(I) chain|collagen alpha-1(I) chain preproprotein|collagen of skin, tendon and bone, alpha-1 chain|pro-alpha-1 collagen type 1 |
Swissprots | Q7KZ34 Q13903 Q13902 Q59F64 Q8N473 Q16050 Q15201 Q14992 Q13896 Q14037 Q15176 Q9UML6 Q9UMM7 Q7KZ30 Q8IVI5 P78441 O76045 P02452 |
Accessions | AAA51847 AAA51992 AAA51993 AAA52036 AAA52052 AAA75386 AAB26324 AAB59363 AAB59373 AAB94054 AAD32608 AGO43920 CAA25082 CAA25394 CCO13712 CDL93516 CDM55394 CDM55575 EAW94630 EAW94631 P02452 AB209597 BAD92834 AK297731 BAH12658 BC036531 AAH36531 DQ590066 DQ893571 ABM84497 EU176569 ABW03370 J00110 AAA52289 J00111 AAA52290 J00112 AAA52291 J00113 AAN86574 JQ236861 AFD28984 K01228 AAA51995 M32798 AAA52049 M36546 AAA60150 S64596 AAB27856 S64717 AAB27677 S67495 AAB20350 X06269 CAA29605 X07884 CAA30731 Z74615 CAA98968 XM_005257058 XP_005257115 XM_005257059 XP_005257116 XM_011524341 XP_011522643 NM_000088 NP_000079 |
Function | Type I collagen is a member of group I collagen (fibrillar forming collagen). |
Subcellular Location | Secreted, extracellular space, extracellular matrix {ECO:0000255|PROSITE-ProRule:PRU00793}. |
Tissue Specificity | Forms the fibrils of tendon, ligaments and bones. In bones the fibrils are mineralized with calcium hydroxyapatite. |
Top Pathways | Focal adhesion, ECM-receptor interaction, Amoebiasis, Protein digestion and absorption, PI3K-Akt signaling pathway |
COL1A (COL-1) - sc-59772 from Santa Cruz Biotechnology
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COL1A1 (C-18) - sc-8784 from Santa Cruz Biotechnology
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COL1A1 (D-13) - sc-25974 from Santa Cruz Biotechnology
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COL1A1 (H-197) - sc-28657 from Santa Cruz Biotechnology
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COL1A1 (L-19) - sc-8783 from Santa Cruz Biotechnology
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Pro-COL1A1 (A-17) - sc-25973 from Santa Cruz Biotechnology
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Pro-COL1A1 (N-17) - sc-8782 from Santa Cruz Biotechnology
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COL1A2 (M-19) - sc-8788 from Santa Cruz Biotechnology
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Anti-Collagen I + Collagen III antibody - ab36065 from Abcam
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Anti-Collagen I + II + III + IV + V antibody - ab24117 from Abcam
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Anti-Collagen I + II + III + IV + V antibody - ab36064 from Abcam
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Anti-Collagen I + II + III antibody [NLI/22] - ab53925 from Abcam
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Anti-Collagen I antibody - ab19811 from Abcam
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Anti-Collagen I antibody [3G3] - ab88147 from Abcam
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Anti-Collagen I antibody [4F6] - ab88288 from Abcam
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Anti-Collagen I antibody (Biotin) - ab24821 from Abcam
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Anti-PICP antibody [002-18] - ab76102 from Abcam
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Anti-PICP antibody [8] - ab17202 from Abcam
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Anti-PICP antibody [BTE 002-32] - ab23415 from Abcam
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Anti-Procollagen Type 1 antibody [2Q576] - ab64409 from Abcam
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Anti-COL1A1 / Collagen I Alpha 1 Antibody (aa34-47) - LS-C2964 from LifeSpan Bioscience
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Anti-COL1A1 / Collagen I Alpha 1 Antibody (DY550) - LS-C180737 from LifeSpan Bioscience
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Anti-COL1A1 / Collagen I Alpha 1 Antibody (DY488) - LS-C180736 from LifeSpan Bioscience
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Anti-COL1A1 / Collagen I Alpha 1 Antibody (DY650) - LS-C180735 from LifeSpan Bioscience
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Anti-COL1A1 / Collagen I Alpha 1 Antibody (Biotin) - LS-C180734 from LifeSpan Bioscience
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