TRPV1

Gene Symbol TRPV1
Entrez Gene 100008926
Alt Symbol -
Species Rabbit
Gene Type protein-coding
Description transient receptor potential cation channel, subfamily V, member 1
Other Description OTRPC1|osm-9-like TRP channel 1|transient receptor potential cation channel subfamily V member 1|transient receptor potential vanilloid type 1|vanilloid receptor 1
Swissprots Q6RX08
Accessions Q6RX08 AY487342 AAR34458 NM_001082166 NP_001075635
Function Ligand-activated non-selective calcium permeant cation channel involved in detection of noxious chemical and thermal stimuli. Seems to mediate proton influx and may be involved in intracellular acidosis in nociceptive neurons. Involved in mediation of inflammatory pain and hyperalgesia. Sensitized by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases, which involves PKC isozymes and PCL. Can be activated by endogenous compounds, including 12- hydroperoxytetraenoic acid and bradykinin. Acts as ionotropic endocannabinoid receptor with central neuromodulatory effects. Triggers a form of long-term depression (TRPV1-LTD) mediated by the endocannabinoid anandamine in the hippocampus and nucleus accumbens by affecting AMPA receptors endocytosis (By similarity). Activation by vanilloids, like capsaicin, and temperatures higher than 42 degrees Celsius, exhibits a time- and Ca(2+)-dependent outward rectification, followed by a long-lasting refractory state. Mil
Subcellular Location Cell junction, synapse, postsynaptic cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cell projection, dendritic spine membrane {ECO:0000250}; Multi- pass membrane protein {ECO:0000250}. Cell membrane; Multi-pass membrane protein. Note=Mostly, but not exclusively expressed in postsynaptic dendritic spines. {ECO:0000250}.
Top Pathways Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction

Transient receptor potential cation channel subfamily V member 1, Trpv1, Rabbit, ELISA Kit - E12152Rb from ARP American Research Products

Category ELISA Kit
Prices $915.00
Sizes 96 t

Transient receptor potential cation channel, subfamily V, member 1, Rabbit, ELISA Kit - E04T0506 from ARP American Research Products

Category ELISA Kit
Prices $535.00, $735.00
Sizes 48 t, 96 t

transient receptor potential cation channel, subfamily V, member 1, ELISA Kit - MBS917556 from MyBioSource

Category ELISA Kit
Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00
Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity The minimum detectable dose of rat TRPV1 is typically less than 7 pg/ml.The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations.
Range 28 pg/ml -1800 pg/ml.

Rat Transient receptor potential cation channel subfamily V member 1(TRPV1) ELISA kit - CSB-EL025093RA from Cusabio

Category ELISA Kit
Sensitivity 7 pg/ml
Range 28 pg/ml-1800 pg/ml

Rabbit Trpv1 ELISA Kit - E101375 from Biobool

Category ELISA Kit

TRPV1 ELISA Kit (Rat) (OKCA01007) - OKCA01007 from Aviva Systems Biology

Category ELISA Kit
Prices $590.00
Sizes 96 wells
Sensitivity 7 pg/mL
Range 28 pg/mL-1,800 pg/mL
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