| Gene Symbol |
CTNNAL1
|
| Entrez Gene |
8727
|
| Alt Symbol |
ACRP, CLLP, alpha-CATU
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
catenin (cadherin-associated protein), alpha-like 1
|
| Other Description |
alpha-catenin-related protein|alpha-catulin|alpha2-catulin|catenin alpha-like protein 1
|
| Swissprots |
Q53FQ2 Q5JTQ7 O76084 B5BU47 Q9UBT7 Q9Y401 Q5JTQ8
|
| Accessions |
AAF07820 AAF07821 AAR92479 EAW59035 EAW59036 EAW59037 Q9UBT7 AB451283 BAG70097 AB451415 BAG70229 AF006070 AAC26011 AF030233 AAC83460 AF080071 AAC69576 AF135021 AAF07819 AI148526 AK022539 AK022834 AK022926 BAG51138 AK123916 AK223230 BAD96950 AK314677 BAG37231 AL050016 CAB43238 BC117208 AAI17209 BC117234 AAI17235 BU677451 DB457537 HQ258655 ADR83406 U97067 AAC27693 XM_005252291 XP_005252348 XM_011519161 XP_011517463 XM_011519162 XP_011517464 XM_011519163 XP_011517465 XR_929869 NM_001286974 NP_001273903 NM_003798 NP_003789
|
| Function |
May modulate the Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor (ARHGEF1).
|
| Subcellular Location |
Cytoplasm, cytoskeleton {ECO:0000269|PubMed:12270917}. Cell membrane {ECO:0000269|PubMed:12270917}; Peripheral membrane protein {ECO:0000269|PubMed:12270917}.
|
| Tissue Specificity |
Widely expressed. Expressed at lower level in neural tissues and at the highest level in the adrenal gland. {ECO:0000269|PubMed:10542337, ECO:0000269|PubMed:12270917, ECO:0000269|PubMed:9806841}.
|
![Western Blot: CTNNAL1 Overexpression Lysate (Adult Normal) [NBP2-07952] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for CTNNAL1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/4200_CTNNAL1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-07952-img0001.jpg)