| Gene Symbol |
PGAM1
|
| Entrez Gene |
5223
|
| Alt Symbol |
HEL-S-35, PGAM-B, PGAMA
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
phosphoglycerate mutase 1 (brain)
|
| Other Description |
BPG-dependent PGAM 1|epididymis secretory protein Li 35|phosphoglycerate mutase 1|phosphoglycerate mutase A, nonmuscle form|phosphoglycerate mutase isozyme B
|
| Swissprots |
Q9BWC0 P18669
|
| Accessions |
CBX85739 CBX85910 EAW49937 EAW49938 EAW49939 EAW49940 EAW49941 EAW49942 EAW49943 EAW49944 P18669 AK223096 BAD96816 AK292216 BAF84905 AK293023 BAF85712 AK295991 BAG58766 AK296619 BAG59227 AK297491 BAG59909 AK312351 BAG35272 AK315910 BAH14281 AY007118 AAG01990 BC000455 AAH00455 BC010038 AAH10038 BC011678 AAH11678 BC053356 AAH53356 BC062302 AAH62302 BC066959 AAH66959 BC073742 AAH73742 BC157873 AAI57874 CR541659 CAG46460 CR541744 CAG46544 DQ893065 ABM83991 DQ896318 ABM87317 EU794644 ACJ13698 J04173 AAA60071 NM_002629 NP_002620
|
| Function |
Interconversion of 3- and 2-phosphoglycerate with 2,3- bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 5.4.2.4 (synthase) and EC 3.1.3.13 (phosphatase), but with a reduced activity.
|
| Tissue Specificity |
In mammalian tissues there are two types of phosphoglycerate mutase isozymes: type-M in muscles and type-B in other tissues.
|
| Top Pathways |
Glycolysis / Gluconeogenesis, Glycine, serine and threonine metabolism, Central carbon metabolism in cancer, Glucagon signaling pathway, Biosynthesis of amino acids
|
![Western Blot: PGAM1 Overexpression Lysate (Adult Normal) [NBL1-14323] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for PGAM1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/2241_PGAM1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-14323-img0002.jpg)