Gene Symbol | TCN2 |
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Entrez Gene | 6948 |
Alt Symbol | D22S676, D22S750, II, TC, TC II, TC-2, TC2, TCII |
Species | Human |
Gene Type | protein-coding |
Description | transcobalamin II |
Other Description | macrocytic anemia|transcobalamin II; macrocytic anemia|transcobalamin-2|vitamin B12-binding protein 2 |
Swissprots | Q9UDM0 Q9UCI5 P20062 Q9BVI8 Q96FD4 Q9UCI6 |
Accessions | AAB25526 AAC05491 AAG24506 EAW59907 EAW59908 EAW59909 EAW59910 P20062 AK225445 AK313711 BC001176 AAH01176 BC011239 AAH11239 CR456591 CAG30477 CU013191 CAK54622 CU013479 CAK54921 DQ892811 ABM83737 DQ896057 ABM87056 L02647 AAA61056 L02648 AAA61057 M60396 AAA61054 NM_000355 NP_000346 NM_001184726 NP_001171655 NM_001190420 |
Function | Primary vitamin B12-binding and transport protein. Delivers cobalamin to cells. |
Subcellular Location | Secreted. |
Top Pathways | Vitamin digestion and absorption |
Transcobalamin II CRISPR/Cas9 KO Plasmid (h) - sc-417237 from Santa Cruz Biotechnology
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Transcobalamin II HDR Plasmid (h) - sc-417237-HDR from Santa Cruz Biotechnology
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Transcobalamin II Double Nickase Plasmid (h) - sc-417237-NIC from Santa Cruz Biotechnology
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Transcobalamin II Double Nickase Plasmid (h2) - sc-417237-NIC-2 from Santa Cruz Biotechnology
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Transcobalamin II CRISPR Activation Plasmid (h) - sc-417237-ACT from Santa Cruz Biotechnology
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Transcobalamin II CRISPR Activation Plasmid (h2) - sc-417237-ACT-2 from Santa Cruz Biotechnology
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Transcobalamin II Lentiviral Activation Particles (h) - sc-417237-LAC from Santa Cruz Biotechnology
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Transcobalamin II Lentiviral Activation Particles (h2) - sc-417237-LAC-2 from Santa Cruz Biotechnology
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Transcobalamin II siRNA (h) - sc-45320 from Santa Cruz Biotechnology
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Transcobalamin II shRNA Plasmid (h) - sc-45320-SH from Santa Cruz Biotechnology
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Transcobalamin II shRNA (h) Lentiviral Particles - sc-45320-V from Santa Cruz Biotechnology
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Transcobalamin II RNAi - H00006948-R01 from Novus Biologicals
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MISSION® esiRNA - EHU044321 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN21160 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21160 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04424 from Sigma-Aldrich
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TCN2 siRNA (Human) - CRH4765 from Cohesion Biosciences
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TCN2 - MBS8219328 from MyBioSource
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shRNA set against Human TCN2 (NM_000355.3) - SHH425016 from Creative biogene
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Human TCN2 siRNA - orb265267 from Biorbyt
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TCN2 shRNA Plasmid (Human) - CHH4765 from Cohesion Biosciences
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TCN2 miRNA 3'UTR clone - MiUTR3H-12898 from Creative biogene
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