| Gene Symbol |
NAALADL1
|
| Entrez Gene |
10004
|
| Alt Symbol |
I100, NAALADASEL
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
N-acetylated alpha-linked acidic dipeptidase-like 1
|
| Other Description |
100 kDa ileum brush border membrane protein|N-acetylated-alpha-linked acidic dipeptidase-like protein|NAALADase L|ileal dipeptidylpeptidase|ileal peptidase I100
|
| Swissprots |
C9J964 Q9UQQ1 C9JL35 C9J8A1 C9JSN0 O43176
|
| Accessions |
EAW74340 Q9UQQ1 AF010141 AAB87645 AJ012371 CAB39968 AK309536 AK311090 BC140321 AAI40322 BC143643 BC143644 BG757994 BM681269 XM_011544706 XP_011543008 XM_011544707 XP_011543009 XM_011544708 XP_011543010 XM_011544709 XP_011543011 XM_011544710 XP_011543012 XM_011544711 XP_011543013 XM_011544712 XP_011543014 XR_949724 XR_949725 XR_949727 XR_949728 XR_949729 XR_949730 NM_005468 NP_005459
|
| Function |
NAALADase-like activity unknown. Has no NAAG hydrolyzing activity. Exhibits a dipeptidyl-peptidase IV type activity. In vitro, cleaves Gly-Pro-AMC (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Apical cell membrane; Single-pass type II membrane protein. Note=Ileal brush border membrane.
|
| Tissue Specificity |
Mainly expressed in the distal small intestine. Also expressed in the spleen and testis. Weak expression in the brain, locating mainly to the brain stem, amygdala, thalamus and ventral striatum. Isoform 2 and 3 isoform 3 are found in the small intestine and colon.
|