| Gene Symbol |
TCEB3B
|
| Entrez Gene |
51224
|
| Alt Symbol |
ELOA2, HsT832, TCEB3L
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
transcription elongation factor B polypeptide 3B (elongin A2)
|
| Other Description |
RNA polymerase II transcription factor SIII subunit A2|elongin-A2|transcription elongation factor (SIII) elongin A2 elongin A2
|
| Swissprots |
Q8IYF1 Q9P2V9
|
| Accessions |
CBH19467 CBH30672 EAW62900 Q8IYF1 AB030834 BAA90665 AK314984 BAG37483 BC036022 AAH36022 BC103911 AAI03912 JF432262 ADZ15479 NM_016427 NP_057511
|
| Function |
SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A2 is transcriptionally active but its transcription activity is not enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex). {ECO:0000269|PubMed:10692460}.
|
| Subcellular Location |
Nucleus {ECO:0000305}.
|
| Tissue Specificity |
Specifically expressed in testis. {ECO:0000269|PubMed:10692460}.
|