| Gene Symbol |
Hlcs
|
| Entrez Gene |
110948
|
| Alt Symbol |
410I21.SP6, D16Jhu34
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
holocarboxylase synthetase (biotin- [propriony-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase)
|
| Other Description |
biotin apo-protein ligase|biotin- [propriony-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase|biotin--protein ligase
|
| Swissprots |
Q920N2
|
| Accessions |
EDL03749 EDL03750 Q920N2 AB066227 BAB68213 AK052424 AK158212 BAE34407 AK164351 AK168925 BAE40738 BC037760 BC050090 AAH50090 XM_006522850 XP_006522913 XM_006522851 XP_006522914 XM_006522852 XP_006522915 XM_006522853 XP_006522916 XM_006522854 XP_006522917 XM_006522855 XP_006522918 XM_006522856 XP_006522919 XM_006523155 XP_006523218 XM_011251409 XP_011249711 NM_139145 NP_631884
|
| Function |
Post-translational modification of specific protein by attachment of biotin. Acts on various carboxylases such as acetyl- CoA-carboxylase, pyruvate carboxylase, propionyl CoA carboxylase, and 3-methylcrotonyl CoA carboxylase (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm {ECO:0000250}. Mitochondrion {ECO:0000250}.
|
| Top Pathways |
Biotin metabolism
|