| Gene Symbol |
RIN3
|
| Entrez Gene |
79890
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
Ras and Rab interactor 3
|
| Other Description |
RAB5 interacting protein 3|ras and Rab interactor 3|ras interaction/interference protein 3
|
| Swissprots |
Q9HAG1 Q8WYP4 Q8TB24 Q76LB3 Q8TEE8 Q9H6A5 Q8NF30
|
| Accessions |
EAW81490 EAW81491 EAW81492 EAW81493 EAW81494 EAW81495 EAW81496 EAW81497 EAW81498 EAW81499 Q8TB24 AB060338 BAB84316 AB081753 BAC16513 AK021762 BAB13888 AK026092 BAB15357 AK074176 BAB85002 AK090451 BAC03432 AK096145 AK128338 BAC87390 BC025248 AAH25248 BC032614 BC034153 BC070062 AAH70062 BX248258 CAD62586 CR936654 CAI56792 XM_011537163 XP_011535465 XM_011537164 XP_011535466 XM_011537165 XP_011535467 NM_024832 NP_079108
|
| Function |
Ras effector protein that functions as a guanine nucleotide exchange (GEF) for RAB5B and RAB31, by exchanging bound GDP for free GTP. Required for normal RAB31 function. {ECO:0000269|PubMed:12972505, ECO:0000269|PubMed:21586568}.
|
| Subcellular Location |
Cytoplasm. Cytoplasmic vesicle. Early endosome. Note=Activation of tyrosine phosphorylation signaling induces translocation to cytoplasmic vesicles.
|
| Tissue Specificity |
Widely expressed. {ECO:0000269|PubMed:12972505}.
|
![Western Blot: RIN3 Overexpression Lysate (Adult Normal) [NBP2-06260] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for RIN3.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/6751_RIN3%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-06260-img0001.jpg)