| Gene Symbol |
NETO2
|
| Entrez Gene |
81831
|
| Alt Symbol |
BTCL2, NEOT2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
neuropilin (NRP) and tolloid (TLL)-like 2
|
| Other Description |
brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2|neuropilin and tolloid-like protein 2
|
| Swissprots |
Q96SP4 Q7Z381 Q8ND51 J3KNF1 Q9NVY8 Q8NC67
|
| Accessions |
CAF86961 EAW82695 EAW82696 Q8NC67 AK001292 BAA91604 AK027478 BAB55141 AK027630 BAB55247 AK074937 BAC11303 AK297408 BAH12573 AL834404 CAD39066 AY358718 AAQ89080 BC012381 AAH12381 BC065504 BC098380 BC108727 AAI08728 BC152765 AAI52766 BC156955 AAI56956 BX538063 CAD97994 CR457255 CAG33536 DA117339 XM_006721289 XP_006721352 XM_006721291 XP_006721354 XM_006721292 XP_006721355 NM_001201477 NP_001188406 NM_018092 NP_060562
|
| Function |
Accessory subunit of neuronal kainate-sensitive glutamate receptors, GRIK2 and GRIK3. Increases kainate-receptor channel activity, slowing the decay kinetics of the receptors, without affecting their expression at the cell surface, and increasing the open probability of the receptor channels. Modulates the agonist sensitivity of kainate receptors. Slows the decay of kainate receptor-mediated excitatory postsynaptic currents (EPSCs), thus directly influencing synaptic transmission (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
|