| Gene Symbol |
CDS2
|
| Entrez Gene |
8760
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
|
| Other Description |
CDP-DAG synthase 2|CDP-DG synthase 2|CDP-DG synthetase 2|CDP-diacylglycerol synthase 2|CDP-diglyceride diphosphorylase 2|CDP-diglyceride pyrophosphorylase 2|CDP-diglyceride synthase 2|CDP-diglyceride synthetase 2|CDS 2|CTP:phosphatidate cytidylyltransferase 2|phosphatidate cytidylyltransferase 2
|
| Swissprots |
Q9NTT2 Q5TDY5 Q5TDY4 Q9BYK5 B2RDC6 D3DW04 O95674 Q5TDY3 Q5TDY2
|
| Accessions |
EAX10424 EAX10425 EAX10426 O95674 AF069532 AAC78305 AK001414 BAG50907 AK022998 AK027695 BAG51366 AK091045 AK095430 AK123831 AK130193 AK303426 BAG64477 AK304763 BAG65518 AK315489 BAG37873 BC015432 BC025346 BC025751 AAH25751 BC044234 BP353230 DQ891643 ABM82569 DQ894832 ABM85758 Y16521 CAA76270 XM_006723660 XP_006723723 XM_011529390 XP_011527692 NM_003818 NP_003809
|
| Function |
Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin.
|
| Subcellular Location |
Mitochondrion inner membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}; Matrix side {ECO:0000305}.
|
| Tissue Specificity |
Widely expressed. Expressed in heart, brain and retina, and to a lesser extent in placenta, lung, liver, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:9889000}.
|
| Top Pathways |
Glycerophospholipid metabolism, Phosphatidylinositol signaling system
|
![Western Blot: CDS2 Overexpression Lysate (Adult Normal) [NBP2-07950] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for CDS2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/5864_CDS2%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-07950-img0001.jpg)