Gene Symbol | GAST |
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Entrez Gene | 2520 |
Alt Symbol | GAS |
Species | Human |
Gene Type | protein-coding |
Description | gastrin |
Other Description | preprogastrin |
Swissprots | P01350 P78464 P78463 |
Accessions | AAA52520 AAB19304 AAB59533 BAR63725 CAA25005 CAA25006 CAA25007 EAW60756 P01350 BC069724 AAH69724 BC069762 AAH69762 BM768483 BM768762 HQ448465 ADQ32945 V00511 CAA23769 NM_000805 NP_000796 |
Function | Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine. |
Subcellular Location | Secreted. |
Top Pathways | Gastric acid secretion |
Gastrin CRISPR/Cas9 KO Plasmid (h) - sc-403220 from Santa Cruz Biotechnology
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Gastrin HDR Plasmid (h) - sc-403220-HDR from Santa Cruz Biotechnology
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Gastrin Double Nickase Plasmid (h) - sc-403220-NIC from Santa Cruz Biotechnology
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Gastrin Double Nickase Plasmid (h2) - sc-403220-NIC-2 from Santa Cruz Biotechnology
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Gastrin CRISPR Activation Plasmid (h) - sc-403220-ACT from Santa Cruz Biotechnology
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Gastrin CRISPR Activation Plasmid (h2) - sc-403220-ACT-2 from Santa Cruz Biotechnology
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Gastrin Lentiviral Activation Particles (h) - sc-403220-LAC from Santa Cruz Biotechnology
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Gastrin Lentiviral Activation Particles (h2) - sc-403220-LAC-2 from Santa Cruz Biotechnology
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Gastrin siRNA (h) - sc-37103 from Santa Cruz Biotechnology
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Gastrin shRNA Plasmid (h) - sc-37103-SH from Santa Cruz Biotechnology
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Gastrin shRNA (h) Lentiviral Particles - sc-37103-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU055831 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9145 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9145 from Sigma-Aldrich
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GAST siRNA (Human) - CRH1666 from Cohesion Biosciences
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GAST - MBS8235265 from MyBioSource
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Gastrin CRISPR/Cas9 KO Plasmid (h2) - sc-403220-KO-2 from Santa Cruz Biotechnology
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Gastrin HDR Plasmid (h2) - sc-403220-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human GAST (NM_000805.4) - SHH299514 from Creative biogene
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Human GAST siRNA - orb262168 from Biorbyt
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GAST shRNA Plasmid (Human) - CHH1666 from Cohesion Biosciences
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