Gene Symbol | CLUH |
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Entrez Gene | 23277 |
Alt Symbol | CLU1, KIAA0664 |
Species | Human |
Gene Type | protein-coding |
Description | clustered mitochondria (cluA/CLU1) homolog |
Other Description | clustered mitochondria protein homolog |
Swissprots | Q8N4U7 Q6AHY2 Q6P3X7 Q9H979 Q9BTA3 O75153 Q6ZUG8 |
Accessions | EAW90532 EAW90533 EAW90534 O75153 AB014564 BAA31639 AK023003 AK074252 AK093541 AK125717 AK308854 AW291521 BC004266 AAH04266 BC033614 AAH33614 BC063786 AAH63786 BC156057 AAI56058 BC156940 AAI56941 BX648864 CR627449 CAH10532 XM_011523768 XP_011522070 NM_015229 NP_056044 |
Function | mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria. Specifically binds mRNAs of nuclear- encoded mitochondrial proteins in the cytoplasm and regulates transport or translation of these transcripts close to mitochondria, playing a role in mitochondrial biogenesis. {ECO:0000255|HAMAP-Rule:MF_03013, ECO:0000269|PubMed:25349259}. |
Subcellular Location | Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03013}. Cytoplasmic granule {ECO:0000269|PubMed:25349259}. Note=A fraction colocalizes with tyrosinated tubulin and can be detected close to mitochondria. {ECO:0000269|PubMed:25349259}. |
KIAA0664 CRISPR/Cas9 KO Plasmid (h) - sc-407383 from Santa Cruz Biotechnology
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KIAA0664 HDR Plasmid (h) - sc-407383-HDR from Santa Cruz Biotechnology
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KIAA0664 Double Nickase Plasmid (h) - sc-407383-NIC from Santa Cruz Biotechnology
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KIAA0664 Double Nickase Plasmid (h2) - sc-407383-NIC-2 from Santa Cruz Biotechnology
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KIAA0664 CRISPR Activation Plasmid (h) - sc-407383-ACT from Santa Cruz Biotechnology
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KIAA0664 CRISPR Activation Plasmid (h2) - sc-407383-ACT-2 from Santa Cruz Biotechnology
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KIAA0664 Lentiviral Activation Particles (h) - sc-407383-LAC from Santa Cruz Biotechnology
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KIAA0664 Lentiviral Activation Particles (h2) - sc-407383-LAC-2 from Santa Cruz Biotechnology
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CLU1 siRNA (h) - sc-93884 from Santa Cruz Biotechnology
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CLU1 shRNA Plasmid (h) - sc-93884-SH from Santa Cruz Biotechnology
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CLU1 shRNA (h) Lentiviral Particles - sc-93884-V from Santa Cruz Biotechnology
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eIF3X RNAi - H00023277-R01 from Novus Biologicals
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MISSION® esiRNA - EHU009381 from Sigma-Aldrich
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MISSION® esiRNA - EHU005821 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN11088 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11088 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR08667 from Sigma-Aldrich
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CLUH siRNA (Human) - CRH8146 from Cohesion Biosciences
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CLUH - MBS8212626 from MyBioSource
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KIAA0664 CRISPR/Cas9 KO Plasmid (h2) - sc-407383-KO-2 from Santa Cruz Biotechnology
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KIAA0664 HDR Plasmid (h2) - sc-407383-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human KIAA0664 (NM_015229.3) - SHH324595 from Creative biogene
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Human CLUH siRNA - orb268648 from Biorbyt
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CLUH shRNA Plasmid (Human) - CHH8146 from Cohesion Biosciences
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KIAA0664 miRNA 3'UTR clone - MiUTR1H-05222 from Creative biogene
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