RREB1
| Gene Symbol | RREB1 |
|---|---|
| Entrez Gene | 6239 |
| Alt Symbol | FINB, HNT, LZ321, RREB-1, Zep-1 |
| Species | Human |
| Gene Type | protein-coding |
| Description | ras responsive element binding protein 1 |
| Other Description | DNA-binding protein|finger protein in nuclear bodies|hindsight homolog|raf-responsive zinc finger protein LZ321|ras-responsive element-binding protein 1|zinc finger motif enhancer binding protein 1|zinc finger motif enhancer-binding protein 1|zinc finger motif-enhancer binding-protein 1 |
| Swissprots | Q6BEP5 E2GM80 A2RRF5 Q6BEP6 Q5VYB2 Q9Y474 Q92766 E2GM81 O75568 Q86SU2 Q6BEP8 O75567 |
| Accessions | EAW55198 EAW55199 EAW55200 Q92766 AB019254 BAD32776 AB019351 BAD32778 AB019352 BAD32779 AF072825 AAC25598 AF072826 AAC26118 AK022160 AK022442 AW505424 BC032062 BC042910 AAH42910 BC111386 BC131599 AAI31600 BC172432 AAI72432 BI818966 BP365591 BX647723 D49835 BAA23165 HM369360 ADO14468 HM369361 ADO14469 U26914 AAB19094 XM_005249275 XP_005249332 XM_006715157 XP_006715220 XM_006715158 XP_006715221 XM_011514791 XP_011513093 XM_011514792 XP_011513094 XM_011514793 XP_011513095 XM_011514794 XP_011513096 XM_011514795 XP_011513097 NM_001003698 NP_001003698 NM_001003699 NP_001003699 NM_001003700 NP_001003700 NM_001168344 NP_001161816 NM_002955 |
| Function | Transcription factor that binds specifically to the RAS- responsive elements (RRE) of gene promoters. May be involved in Ras/Raf-mediated cell differentiation by enhancing calcitonin expression. Represses the angiotensinogen gene. Negatively regulates the transcriptional activity of AR. Potentiates the transcriptional activity of NEUROD1. {ECO:0000269|PubMed:10390538, ECO:0000269|PubMed:12482979, ECO:0000269|PubMed:15067362, ECO:0000269|PubMed:17550981, ECO:0000269|PubMed:8816445, ECO:0000269|PubMed:9305772}. |
| Subcellular Location | Nucleus speckle {ECO:0000269|PubMed:15067362, ECO:0000269|PubMed:17550981, ECO:0000269|PubMed:9305772}. |
| Tissue Specificity | Expressed in heart, placenta, lung, liver, skeletal muscle, kidney and pancreas. Not found in the brain. {ECO:0000269|PubMed:8816445}. |
RREB1 CRISPR/Cas9 KO Plasmid (h) - sc-404819 from Santa Cruz Biotechnology
|
||||||||
RREB1 HDR Plasmid (h) - sc-404819-HDR from Santa Cruz Biotechnology
|
||||||||
RREB1 Double Nickase Plasmid (h) - sc-404819-NIC from Santa Cruz Biotechnology
|
||||||||
RREB1 Double Nickase Plasmid (h2) - sc-404819-NIC-2 from Santa Cruz Biotechnology
|
||||||||
RREB1 CRISPR Activation Plasmid (h) - sc-404819-ACT from Santa Cruz Biotechnology
|
||||||||
RREB1 CRISPR Activation Plasmid (h2) - sc-404819-ACT-2 from Santa Cruz Biotechnology
|
||||||||
RREB1 Lentiviral Activation Particles (h) - sc-404819-LAC from Santa Cruz Biotechnology
|
||||||||
RREB1 Lentiviral Activation Particles (h2) - sc-404819-LAC-2 from Santa Cruz Biotechnology
|
||||||||
RREB1 siRNA (h) - sc-95379 from Santa Cruz Biotechnology
|
||||||||
RREB1 shRNA Plasmid (h) - sc-95379-SH from Santa Cruz Biotechnology
|
||||||||
RREB1 shRNA (h) Lentiviral Particles - sc-95379-V from Santa Cruz Biotechnology
|
||||||||
RREB1 RNAi - H00006239-R01 from Novus Biologicals
|
||||||||
RREB1 RNAi - H00006239-R02 from Novus Biologicals
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN18683 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18683 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR10876 from Sigma-Aldrich
|
||||||||
RREB1 siRNA (Human) - CRH4202 from Cohesion Biosciences
|
||||||||
RREB1 RNAi - H00006239-R03 from Novus Biologicals
|
||||||||
RREB1 - MBS8229174 from MyBioSource
|
||||||||
shRNA set against Human RREB1 (NM_001003698.3) - SHH399928 from Creative biogene
|
||||||||
RREB1 shRNA Plasmid (Human) - CHH4202 from Cohesion Biosciences
|