| Gene Symbol |
NOS1AP
|
| Entrez Gene |
9722
|
| Alt Symbol |
6330408P19Rik, CAPON
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
nitric oxide synthase 1 (neuronal) adaptor protein
|
| Other Description |
C-terminal PDZ domain ligand of neuronal nitric oxide synthase (CAPON)|C-terminal PDZ ligand of neuronal nitric oxide synthase protein|carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein|ligand of neuronal nitric oxide synthase with carboxyl-terminal PDZ domain|nitric oxide synthase 1 adaptor protein
|
| Swissprots |
Q3T551 O75052 Q5VU95 O43564 B7ZLF5
|
| Accessions |
EAW90700 O75052 AB007933 BAA32309 AF037070 AAC39656 AI198232 AY841899 AAW57298 BC041382 BC111928 AAI11929 BC112295 AAI12296 BC118499 AAI18500 BC143771 AAI43772 BC143780 NM_001126060 NP_001119532 NM_001164757 NP_001158229 NM_014697 NP_055512
|
| Function |
Adapter protein involved in neuronal nitric-oxide (NO) synthesis regulation via its association with nNOS/NOS1. The complex formed with NOS1 and synapsins is necessary for specific NO and synapsin functions at a presynaptic level. Mediates an indirect interaction between NOS1 and RASD1 leading to enhance the ability of NOS1 to activate RASD1. Competes with DLG4 for interaction with NOS1, possibly affecting NOS1 activity by regulating the interaction between NOS1 and DLG4 (By similarity). {ECO:0000250}.
|
| Top Pathways |
Circadian entrainment
|
![Western Blot: NOS1AP Overexpression Lysate (Adult Normal) [NBL1-13720] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for NOS1AP.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/5613_NOS1AP%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-13720-img0002.jpg)