Gene Symbol | PDS5B |
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Entrez Gene | 23047 |
Alt Symbol | APRIN, AS3, CG008 |
Species | Human |
Gene Type | protein-coding |
Description | PDS5 cohesin associated factor B |
Other Description | androgen induced inhibitor of proliferation|androgen-induced proliferation inhibitor|androgen-induced prostate proliferative shutoff-associated protein AS3|androgen-induced shutoff 3|sister chromatid cohesion protein PDS5 homolog B |
Swissprots | Q5W0K8 Q5R3S3 Q9Y451 Q9NTI5 Q8IXT6 Q6NSC3 Q9H5N8 Q9Y2I5 |
Accessions | CAI10806 EAX08520 Q9NTI5 AB023196 BAA76823 AK026889 BAB15584 AK128502 AK299340 BAH13007 AL137201 CAB69911 BC026240 BC039256 AAH39256 BC070274 AAH70274 BC172246 AAI72246 BP398054 DA856411 DB456240 JF432219 ADZ15436 U50533 U95825 AAD22134 XM_005266298 XP_005266355 XM_011534999 XP_011533301 XM_011535000 XP_011533302 XM_011535001 XP_011533303 XM_011535002 XP_011533304 NM_015032 NP_055847 NM_015928 |
Function | Regulator of sister chromatid cohesion in mitosis which may stabilize cohesin complex association with chromatin. May couple sister chromatid cohesion during mitosis to DNA replication. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. Plays a role in androgen-induced proliferative arrest in prostate cells. {ECO:0000269|PubMed:10963680, ECO:0000269|PubMed:15855230, ECO:0000269|PubMed:19696148}. |
Subcellular Location | Nucleus {ECO:0000250|UniProtKB:Q6TRW4}. |
Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:9459187}. |
Human PDS5B protein fragment - ab153203 from Abcam
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PDS5B / AS3 Antibody Blocking Peptide - LS-E21328 from LifeSpan Bioscience
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Recombinant Human APRIN Protein - H00023047-Q01 from Novus Biologicals
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PDS5B Blocking Peptide - 33R-1917 from Fitzgerald
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PDS5B / APRIN - H00023047-Q01-10 from Acris Antibodies
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PDS5B / APRIN - H00023047-Q01-25 from Acris Antibodies
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PDS5B fusion protein - Ag8301 from Proteintech Group
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PDS5B fusion protein - ag3800 from Proteintech Group
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Recombinant Human PDS5B, His-tagged - PDS5B-1629H from Creative Biomart
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Recombinant Human Sister chromatid cohesion protein PDS5 homolog B(PDS5B) ,parti - CSB-YP889108HU CSB-EP889108HU CSB-BP889108HU CSB-MP889108HU from Cusabio
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APRIN Recombinant Protein Antigen - NBP1-90122PEP from Novus Biologicals
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APRIN Recombinant Protein Antigen - NBP1-90121PEP from Novus Biologicals
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PDS5B-Blocking-Peptide-C-Term - BP21942b from Abgent, a WuXi AppTec company
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PDS5B Peptide, Human - M34GP11555H from Creative Peptides
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Sister chromatid cohesion protein PDS5 homolog B (PDS5B), partial, Recombinant Protein - MBS1333194 from MyBioSource
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PDS5B fusion protein - Ag27977 from Proteintech Group
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Recombinant Human APRIN protein, GST-tagged - APRIN-728H from Creative Biomart
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