Gene Symbol | GNAO1 |
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Entrez Gene | 2775 |
Alt Symbol | EIEE17, G-ALPHA-o, GNAO |
Species | Human |
Gene Type | protein-coding |
Description | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O |
Other Description | guanine nucleotide-binding protein G(o) subunit alpha |
Swissprots | Q8TD72 Q9UMV4 P29777 P09471 |
Accessions | AAA52584 AAA52585 AAA52586 EAW82849 EAW82850 P09471 AF493894 AAM12608 AF493895 AAM12609 AK056008 BAG51601 AK295680 BAG58537 AL512686 BC012202 BC030027 AAH30027 BX647214 CAH10548 CR936770 DA115582 DA500625 DA529437 EU832446 ACE87618 EU832529 ACE86931 M19182 Y18213 CAB46639 XM_011523003 XP_011521305 NM_020988 NP_066268 NM_138736 NP_620073 |
Function | Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(o) protein function is not clear. Stimulated by RGS14. |
Subcellular Location | Cell membrane {ECO:0000250}. |
Top Pathways | Estrogen signaling pathway, Alcoholism, Circadian entrainment, Rap1 signaling pathway, Oxytocin signaling pathway |
G α o CRISPR/Cas9 KO Plasmid (h) - sc-400897 from Santa Cruz Biotechnology
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G α o HDR Plasmid (h) - sc-400897-HDR from Santa Cruz Biotechnology
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G α o Double Nickase Plasmid (h) - sc-400897-NIC from Santa Cruz Biotechnology
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G α o Double Nickase Plasmid (h2) - sc-400897-NIC-2 from Santa Cruz Biotechnology
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G α o CRISPR Activation Plasmid (h) - sc-400897-ACT from Santa Cruz Biotechnology
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G α o CRISPR Activation Plasmid (h2) - sc-400897-ACT-2 from Santa Cruz Biotechnology
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G α o Lentiviral Activation Particles (h) - sc-400897-LAC from Santa Cruz Biotechnology
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G α o Lentiviral Activation Particles (h2) - sc-400897-LAC-2 from Santa Cruz Biotechnology
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G α o siRNA (h) - sc-29326 from Santa Cruz Biotechnology
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G α o shRNA Plasmid (h) - sc-29326-SH from Santa Cruz Biotechnology
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G α o shRNA (h) Lentiviral Particles - sc-29326-V from Santa Cruz Biotechnology
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GO Protein alpha RNAi - H00002775-R02 from Novus Biologicals
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GO Protein alpha RNAi - H00002775-R01 from Novus Biologicals
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MISSION® esiRNA - EHU067621 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9408 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9408 from Sigma-Aldrich
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GNAO1 siRNA (Human) - CRH1845 from Cohesion Biosciences
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GNAO1 - MBS8229953 from MyBioSource
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Gα o CRISPR/Cas9 KO Plasmid (h2) - sc-400897-KO-2 from Santa Cruz Biotechnology
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Gα o HDR Plasmid (h2) - sc-400897-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human GNAO1 (NM_020988.2) - SHH304662 from Creative biogene
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shRNA set against Human GNAO1(NM_138736.2) - SHH091433 from Creative biogene
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shRNA set against Human GNAO1(NM_020988.2) - SHH091435 from Creative biogene
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shRNA set against Human GNAO1(NM_138736.2) - SHH091471 from Creative biogene
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GNAO1 shRNA Plasmid (Human) - CHH1845 from Cohesion Biosciences
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