Gene Symbol | IQSEC2 |
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Entrez Gene | 23096 |
Alt Symbol | BRAG1, MRX1 |
Species | Human |
Gene Type | protein-coding |
Description | IQ motif and Sec7 domain 2 |
Other Description | IQ motif and SEC7 domain-containing protein 2|brefeldin A resistant Arf-guanine nucleotide exchange factor 1|brefeldin A resistant Arf-guanine nucleotide exchange factor 1b|brefeldin A resistant Arf-guanine nucleotide exchange factor 1c |
Swissprots | Q5JU85 B3KT97 Q5JUX1 O60275 C7SDG1 |
Accessions | CAI42091 CCQ43090 EAW93147 Q5JU85 AB011094 BAA25448 AK095232 BAG53009 BC038213 BC044252 BC108674 BC156683 AAI56684 BX119489 DA433389 FJ154890 ACR15955 FJ154891 ACR15956 FJ154892 ACR15957 FJ154893 ACR15958 XM_006724579 XP_006724642 XM_006724580 XP_006724643 XM_006724581 XP_006724644 XM_006724582 XP_006724645 XM_006724583 XP_006724646 XM_006724584 XP_006724647 XM_011530772 XP_011529074 XM_011530773 XP_011529075 XM_011530774 XP_011529076 XM_011530775 XP_011529077 XM_011530776 XP_011529078 XM_011530777 XP_011529079 XR_938365 NM_001111125 NP_001104595 NM_001243197 NP_001230126 NM_015075 NP_055890 |
Subcellular Location | Cytoplasm {ECO:0000305}. |
Tissue Specificity | Expressed in brain, kidney and small intestine. Weakly expressed in placenta, pancreas, ovary, prostate and liver. {ECO:0000269|PubMed:9628581}. |
Top Pathways | Endocytosis |
IQSEC2 CRISPR/Cas9 KO Plasmid (h) - sc-407947 from Santa Cruz Biotechnology
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IQSEC2 HDR Plasmid (h) - sc-407947-HDR from Santa Cruz Biotechnology
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IQSEC2 Double Nickase Plasmid (h) - sc-407947-NIC from Santa Cruz Biotechnology
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IQSEC2 Double Nickase Plasmid (h2) - sc-407947-NIC-2 from Santa Cruz Biotechnology
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IQSEC2 CRISPR Activation Plasmid (h) - sc-407947-ACT from Santa Cruz Biotechnology
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IQSEC2 CRISPR Activation Plasmid (h2) - sc-407947-ACT-2 from Santa Cruz Biotechnology
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IQSEC2 Lentiviral Activation Particles (h) - sc-407947-LAC from Santa Cruz Biotechnology
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IQSEC2 Lentiviral Activation Particles (h2) - sc-407947-LAC-2 from Santa Cruz Biotechnology
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IQSEC2 siRNA (h) - sc-91115 from Santa Cruz Biotechnology
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IQSEC2 shRNA Plasmid (h) - sc-91115-SH from Santa Cruz Biotechnology
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IQSEC2 shRNA (h) Lentiviral Particles - sc-91115-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU008851 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10757 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10757 from Sigma-Aldrich
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IQSEC2 siRNA (Human) - CRH7995 from Cohesion Biosciences
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IQSEC2 - MBS8218712 from MyBioSource
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shRNA set against Human IQSEC2 (NM_015075.1) - SHH320449 from Creative biogene
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shRNA set against Human IQSEC2(NM_015075.1) - SHL173424 from Creative biogene
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Human IQSEC2 siRNA - orb268497 from Biorbyt
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IQSEC2 shRNA Plasmid (Human) - CHH7995 from Cohesion Biosciences
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IQSEC2 miRNA 3'UTR clone - MiUTR1H-04984 from Creative biogene
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IQSEC2 miRNA 3'UTR clone - MiUTR3H-02819 from Creative biogene
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