Gene Symbol | MEST |
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Entrez Gene | 4232 |
Alt Symbol | PEG1 |
Species | Human |
Gene Type | protein-coding |
Description | mesoderm specific transcript |
Other Description | mesoderm-specific transcript homolog protein|paternally-expressed gene 1 protein |
Swissprots | B2R6S1 Q6AI49 Q5EB52 O15007 O14973 Q92571 |
Accessions | BAC02716 CAA71631 EAL24086 EAL24087 EAW83765 EAW83766 EAW83767 Q5EB52 AA728839 AK098397 AK298984 BAG61078 AK312688 BAG35568 AU118070 BC002413 AAH02413 BC011908 AAH11908 BC014564 AAH14564 BC018695 AAH18695 BC090049 AAH90049 BG831799 BI459412 BT007056 AAP35705 CN425918 CR457040 CAG33321 CR627364 CAH10465 D78611 BAA11432 D87367 BAA21757 DA487705 DB454206 DC367784 DQ890762 ABM81688 DQ892764 ABM83690 DQ893925 ABM84851 DQ896009 ABM87003 Y11534 CAA72297 XM_011516222 XP_011514524 NM_001253900 NP_001240829 NM_001253901 NP_001240830 NM_001253902 NP_001240831 NM_002402 NP_002393 NM_177524 NP_803490 NM_177525 NP_803491 |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
Tissue Specificity | Highly expressed in hydatidiform moles, but barely expressed in dermoid cysts. Biallelic expression is detected in blood lymphocytes. Seems to imprinted in an isoform- specific manner rather than in a tissue-specific manner in lymphocytes. Isoform 1 is expressed only from the paternal allele. Isoform 2 is expressed from both the paternal allele and the maternal allele. {ECO:0000269|PubMed:8884280, ECO:0000269|PubMed:9192843}. |
Peg1 CRISPR/Cas9 KO Plasmid (h) - sc-410884 from Santa Cruz Biotechnology
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Peg1 HDR Plasmid (h) - sc-410884-HDR from Santa Cruz Biotechnology
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Peg1 Double Nickase Plasmid (h) - sc-410884-NIC from Santa Cruz Biotechnology
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Peg1 Double Nickase Plasmid (h2) - sc-410884-NIC-2 from Santa Cruz Biotechnology
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Peg1 CRISPR Activation Plasmid (h) - sc-410884-ACT from Santa Cruz Biotechnology
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Peg1 CRISPR Activation Plasmid (h2) - sc-410884-ACT-2 from Santa Cruz Biotechnology
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Peg1 Lentiviral Activation Particles (h) - sc-410884-LAC from Santa Cruz Biotechnology
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Peg1 Lentiviral Activation Particles (h2) - sc-410884-LAC-2 from Santa Cruz Biotechnology
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Peg1 siRNA (h) - sc-61315 from Santa Cruz Biotechnology
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Peg1 shRNA Plasmid (h) - sc-61315-SH from Santa Cruz Biotechnology
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Peg1 shRNA (h) Lentiviral Particles - sc-61315-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU086991 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN13214 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND13214 from Sigma-Aldrich
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MEST siRNA (Human) - CRH2875 from Cohesion Biosciences
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shRNA set against Human MEST (NM_177525.2) - SHH340535 from Creative biogene
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Human MEST siRNA - orb263377 from Biorbyt
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MEST shRNA Plasmid (Human) - CHH2875 from Cohesion Biosciences
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MEST miRNA 3'UTR clone - MiUTR3H-03819 from Creative biogene
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MEST miRNA 3'UTR clone - MiUTR3H-03820 from Creative biogene
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MEST miRNA 3'UTR clone - MiUTR3H-03821 from Creative biogene
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