Gene Symbol |
INHBA
|
Entrez Gene |
3624
|
Alt Symbol |
EDF, FRP
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
inhibin, beta A
|
Other Description |
FSH-releasing protein|Inhibin, beta-1|activin beta-A chain|erythroid differentiation factor|erythroid differentiation protein|follicle-stimulating hormone-releasing protein|inhibin beta A chain|inhibin, beta A (activin A, activin AB alpha polypeptide)
|
Swissprots |
P08476 Q14599
|
Accessions |
AAQ96861 CAA01159 CAA28041 CAA40805 CAA40806 CAJ84003 EAL24001 EAW94139 EAW94140 EAW94141 P08476 AF218018 AAG17260 AK222742 BAD96462 AK290584 BAF83273 AU137531 BC007858 AAH07858 BX648811 CAI46003 D49743 BAA08577 DQ893158 ABM84084 DQ896452 ABM87451 J03634 AAA35787 M13436 AAA59168 X72498 CAA51163 NM_002192 NP_002183
|
Function |
Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
|
Subcellular Location |
Secreted.
|
Top Pathways |
Cytokine-cytokine receptor interaction, TGF-beta signaling pathway, Signaling pathways regulating pluripotency of stem cells
|