Gene Symbol | Gsdma |
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Entrez Gene | 57911 |
Alt Symbol | BB149167, Gsdm, Gsdm1, Gsdma1, H312E |
Species | Mouse |
Gene Type | protein-coding |
Description | gasdermin A |
Other Description | gasdermin 1|gasdermin A1|gasdermin-1|gasdermin-A|gasdermin-A1 |
Swissprots | A3KFN3 Q9EST1 |
Accessions | EDL16157 Q9EST1 AB033595 BAB13697 AK028645 BAC26045 AK028698 BAC26073 AK029062 BAC26272 AK080067 BC140388 AAI40389 BC148684 AAI48685 XM_006533850 XP_006533913 NM_021347 NP_067322 |
Function | Induces apoptosis. {ECO:0000250}. |
Subcellular Location | Cytoplasm, perinuclear region {ECO:0000269|PubMed:10967128}. |
Tissue Specificity | Expressed predominantly in the gastrointestinal (GI) tract and in the skin at a lower level. In the GI tract, the expression is highly restricted to the esophagus and forestomach. {ECO:0000269|PubMed:10967128, ECO:0000269|PubMed:17350798}. |
gasdermin CRISPR/Cas9 KO Plasmid (m) - sc-425460 from Santa Cruz Biotechnology
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gasdermin HDR Plasmid (m) - sc-425460-HDR from Santa Cruz Biotechnology
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gasdermin Double Nickase Plasmid (m) - sc-425460-NIC from Santa Cruz Biotechnology
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gasdermin Double Nickase Plasmid (m2) - sc-425460-NIC-2 from Santa Cruz Biotechnology
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gasdermin CRISPR Activation Plasmid (m) - sc-425460-ACT from Santa Cruz Biotechnology
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gasdermin CRISPR Activation Plasmid (m2) - sc-425460-ACT-2 from Santa Cruz Biotechnology
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gasdermin Lentiviral Activation Particles (m) - sc-425460-LAC from Santa Cruz Biotechnology
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gasdermin Lentiviral Activation Particles (m2) - sc-425460-LAC-2 from Santa Cruz Biotechnology
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gasdermin siRNA (m) - sc-75110 from Santa Cruz Biotechnology
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gasdermin shRNA Plasmid (m) - sc-75110-SH from Santa Cruz Biotechnology
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gasdermin shRNA (m) Lentiviral Particles - sc-75110-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN32883 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND32883 from Sigma-Aldrich
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GSDMA siRNA (Mouse) - CRM6076 from Cohesion Biosciences
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GSDMA - MBS8220188 from MyBioSource
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shRNA set against Mouse GSDMA (NM_021347.4) - SHH308358 from Creative biogene
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GSDMA shRNA Plasmid (Mouse) - CHM6076 from Cohesion Biosciences
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