Gene Symbol | Egf |
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Entrez Gene | 13645 |
Alt Symbol | AI790464 |
Species | Mouse |
Gene Type | protein-coding |
Description | epidermal growth factor |
Other Description | Pro-epidermal growth factor precursor (EGF)|pro-epidermal growth factor |
Swissprots | P01132 Q6P9J2 Q569W5 E9QNX6 |
Accessions | EDL12237 EDL12238 P01132 AK084927 AK085707 AK088408 AK136439 BAE22978 AK142666 AK157778 BC017681 AAH17681 BC060741 AAH60741 BC092277 AAH92277 J00380 AAA37539 V00741 CAA24115 X74038 XM_006500990 XP_006501053 XM_006500991 XP_006501054 XM_011240010 XP_011238312 XM_011240011 XP_011238313 XR_867211 NM_010113 NP_034243 |
Function | EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity). {ECO:0000250}. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Top Pathways | Endocytosis, Rap1 signaling pathway, Hepatitis C, PI3K-Akt signaling pathway, Choline metabolism in cancer |
EGF CRISPR/Cas9 KO Plasmid (m) - sc-420128 from Santa Cruz Biotechnology
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EGF HDR Plasmid (m) - sc-420128-HDR from Santa Cruz Biotechnology
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EGF Double Nickase Plasmid (m) - sc-420128-NIC from Santa Cruz Biotechnology
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EGF Double Nickase Plasmid (m2) - sc-420128-NIC-2 from Santa Cruz Biotechnology
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EGF CRISPR Activation Plasmid (m) - sc-420128-ACT from Santa Cruz Biotechnology
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EGF CRISPR Activation Plasmid (m2) - sc-420128-ACT-2 from Santa Cruz Biotechnology
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EGF Lentiviral Activation Particles (m) - sc-420128-LAC from Santa Cruz Biotechnology
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EGF Lentiviral Activation Particles (m2) - sc-420128-LAC-2 from Santa Cruz Biotechnology
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EGF siRNA (m) - sc-39417 from Santa Cruz Biotechnology
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EGF shRNA Plasmid (m) - sc-39417-SH from Santa Cruz Biotechnology
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EGF shRNA (m) Lentiviral Particles - sc-39417-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU025331 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN30484 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND30484 from Sigma-Aldrich
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EGF siRNA (Mouse) - CRM1152 from Cohesion Biosciences
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EGF - MBS8239883 from MyBioSource
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shRNA set against Mouse EGF (NM_010113.3) - SHH283781 from Creative biogene
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Mouse EGF siRNA - orb280628 from Biorbyt
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EGF shRNA Plasmid (Mouse) - CHM1152 from Cohesion Biosciences
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