Gene Symbol |
Aspa
|
Entrez Gene |
79251
|
Alt Symbol |
-
|
Species |
Rat
|
Gene Type |
protein-coding
|
Description |
aspartoacylase
|
Other Description |
ACY-2|aminoacylase-2
|
Swissprots |
Q6AZ03 Q9R1T5
|
Accessions |
EDM05149 EDM05150 EDM05151 EDM05152 Q9R1T5 AB023432 BAA82801 BC078813 AAH78813 BC078814 AAH78814 FQ232103 XM_006246815 XP_006246877 XM_006246817 XP_006246879 XM_006246818 XP_006246880 NM_024399 NP_077375
|
Function |
Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter (By similarity). {ECO:0000250}.
|
Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:16935940}. Nucleus {ECO:0000269|PubMed:16935940}.
|
Tissue Specificity |
Detected in kidney proximal tubule cells (at protein level). {ECO:0000269|PubMed:16935940}.
|
Top Pathways |
Alanine, aspartate and glutamate metabolism, Histidine metabolism
|