| Gene Symbol | Aspa |
|---|---|
| Entrez Gene | 79251 |
| Alt Symbol | - |
| Species | Rat |
| Gene Type | protein-coding |
| Description | aspartoacylase |
| Other Description | ACY-2|aminoacylase-2 |
| Swissprots | Q6AZ03 Q9R1T5 |
| Accessions | EDM05149 EDM05150 EDM05151 EDM05152 Q9R1T5 AB023432 BAA82801 BC078813 AAH78813 BC078814 AAH78814 FQ232103 XM_006246815 XP_006246877 XM_006246817 XP_006246879 XM_006246818 XP_006246880 NM_024399 NP_077375 |
| Function | Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter (By similarity). {ECO:0000250}. |
| Subcellular Location | Cytoplasm {ECO:0000269|PubMed:16935940}. Nucleus {ECO:0000269|PubMed:16935940}. |
| Tissue Specificity | Detected in kidney proximal tubule cells (at protein level). {ECO:0000269|PubMed:16935940}. |
| Top Pathways | Alanine, aspartate and glutamate metabolism, Histidine metabolism |
CompoZr® Knockout ZFN Kit - CKOZFN50877 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND50877 from Sigma-Aldrich
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ASPA siRNA (Rat) - CRR2193 from Cohesion Biosciences
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ASPA - MBS827753 from MyBioSource
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shRNA set against Rat ASPA (NM_024399.1) - SHH241582 from Creative biogene
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shRNA set against Rat Aspa(NM_024399.1) - SHG077879 from Creative biogene
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Rat ASPA siRNA - orb297042 from Biorbyt
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ASPA shRNA Plasmid (Rat) - CHR2193 from Cohesion Biosciences
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ASPA miRNA 3'UTR clone - MiUTR1R-00420 from Creative biogene
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