Gene Symbol | LIPM |
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Entrez Gene | 340654 |
Alt Symbol | LIPL3, bA304I5.1 |
Species | Human |
Gene Type | protein-coding |
Description | lipase, family member M |
Other Description | lipase M|lipase member M|lipase-like abhydrolase domain-containing protein 3|lipase-like, ab-hydrolase domain containing 3 |
Swissprots | B5MCR3 B2RXK7 Q5VYY2 A6PVS3 |
Accessions | CAD52970 Q5VYY2 BC157888 AAI57889 BC171908 AAI71908 EF426484 ABR08389 XM_011539748 XP_011538050 XM_011539749 XP_011538051 XM_011539750 XP_011538052 XM_011539751 XP_011538053 XM_011539752 XP_011538054 XM_011539753 XP_011538055 NM_001128215 NP_001121687 |
Function | Plays a highly specific role in the last step of keratinocyte differentiation. May have an essential function in lipid metabolism of the most differentiated epidermal layers. {ECO:0000269|PubMed:17562024}. |
Subcellular Location | Secreted {ECO:0000305}. |
Tissue Specificity | Exclusively expressed in the epidermis within the granular keratinocytes. {ECO:0000269|PubMed:17562024}. |
LIPM CRISPR/Cas9 KO Plasmid (h) - sc-415551 from Santa Cruz Biotechnology
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LIPM HDR Plasmid (h) - sc-415551-HDR from Santa Cruz Biotechnology
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LIPM Double Nickase Plasmid (h) - sc-415551-NIC from Santa Cruz Biotechnology
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LIPM Double Nickase Plasmid (h2) - sc-415551-NIC-2 from Santa Cruz Biotechnology
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LIPM CRISPR Activation Plasmid (h) - sc-415551-ACT from Santa Cruz Biotechnology
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LIPM CRISPR Activation Plasmid (h2) - sc-415551-ACT-2 from Santa Cruz Biotechnology
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LIPM Lentiviral Activation Particles (h) - sc-415551-LAC from Santa Cruz Biotechnology
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LIPM Lentiviral Activation Particles (h2) - sc-415551-LAC-2 from Santa Cruz Biotechnology
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LIPM siRNA (h) - sc-90631 from Santa Cruz Biotechnology
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LIPM shRNA Plasmid (h) - sc-90631-SH from Santa Cruz Biotechnology
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LIPM shRNA (h) Lentiviral Particles - sc-90631-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN11749 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11749 from Sigma-Aldrich
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LIPM siRNA (Human) - CRJ7360 from Cohesion Biosciences
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shRNA set against Human Lipm (NM_001128215.1) - SHH330731 from Creative biogene
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Human LIPM siRNA - orb277861 from Biorbyt
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LIPM shRNA Plasmid (Human) - CHJ7360 from Cohesion Biosciences
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