Gene Symbol | PPIG |
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Entrez Gene | 9360 |
Alt Symbol | CARS-Cyp, CYP, SCAF10, SRCyp |
Species | Human |
Gene Type | protein-coding |
Description | peptidylprolyl isomerase G (cyclophilin G) |
Other Description | CARS-cyclophilin|CASP10|Clk-associating RS-cyclophilin|PPIase G|SR-cyclophilin|SR-cyp|SR-related CTD-associated factor 10|cyclophilin G|peptidyl-prolyl cis-trans isomerase G|peptidyl-prolyl isomerase G (cyclophilin G)|rotamase G |
Swissprots | Q96DG9 Q53R40 Q53SN4 O00706 Q13427 D3DPC6 D3DPC5 |
Accessions | AAY24119 AAY24233 EAX11266 EAX11267 EAX11268 EAX11269 EAX11270 Q13427 AK124958 AK307552 BC001555 AAH01555 BC063711 AAH63711 BC073875 AAH73875 BC109373 AAI09374 BC111693 AAI11694 BG615922 CA418130 U40763 AAB40347 X99717 CAA68053 XM_005246966 XP_005247023 XM_005246967 XP_005247024 XM_011512192 XP_011510494 NM_004792 NP_004783 |
Function | PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be implicated in the folding, transport, and assembly of proteins. May play an important role in the regulation of pre-mRNA splicing. |
Subcellular Location | Nucleus matrix {ECO:0000269|PubMed:15358154}. Nucleus speckle {ECO:0000269|PubMed:15358154}. Note=Colocalizes with RNA splicing factors at nuclear speckles. |
Tissue Specificity | Ubiquitous. |
Cyclophilin G CRISPR/Cas9 KO Plasmid (h) - sc-406523 from Santa Cruz Biotechnology
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Cyclophilin G HDR Plasmid (h) - sc-406523-HDR from Santa Cruz Biotechnology
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Cyclophilin G Double Nickase Plasmid (h) - sc-406523-NIC from Santa Cruz Biotechnology
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Cyclophilin G Double Nickase Plasmid (h2) - sc-406523-NIC-2 from Santa Cruz Biotechnology
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Cyclophilin G CRISPR Activation Plasmid (h) - sc-406523-ACT from Santa Cruz Biotechnology
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Cyclophilin G CRISPR Activation Plasmid (h2) - sc-406523-ACT-2 from Santa Cruz Biotechnology
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Cyclophilin G Lentiviral Activation Particles (h) - sc-406523-LAC from Santa Cruz Biotechnology
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Cyclophilin G Lentiviral Activation Particles (h2) - sc-406523-LAC-2 from Santa Cruz Biotechnology
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Cyclophilin G siRNA (h) - sc-94752 from Santa Cruz Biotechnology
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Cyclophilin G shRNA Plasmid (h) - sc-94752-SH from Santa Cruz Biotechnology
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Cyclophilin G shRNA (h) Lentiviral Particles - sc-94752-V from Santa Cruz Biotechnology
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Caspase-10/FLICE2 RNAi - H00000843-R03 from Novus Biologicals
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Caspase-10/FLICE2 RNAi - H00000843-R02 from Novus Biologicals
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PPIG RNAi - H00009360-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN17229 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17229 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00585 from Sigma-Aldrich
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PPIG siRNA (Human) - CRH6196 from Cohesion Biosciences
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shRNA set against Human PPIG (NM_004792.2) - SHH380668 from Creative biogene
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shRNA set against Human PPIG(NM_004792.2) - SHG141657 from Creative biogene
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Human PPIG siRNA - orb266698 from Biorbyt
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PPIG shRNA Plasmid (Human) - CHH6196 from Cohesion Biosciences
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PPIG miRNA 3'UTR clone - MiUTR1H-08155 from Creative biogene
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