Gene Symbol | CD8A |
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Entrez Gene | 925 |
Alt Symbol | CD8, Leu2, MAL, p32 |
Species | Human |
Gene Type | protein-coding |
Description | CD8a molecule |
Other Description | CD8 antigen, alpha polypeptide (p32)|Leu2 T-lymphocyte antigen|OKT8 T-cell antigen|T cell co-receptor|T-cell antigen Leu2|T-cell surface glycoprotein CD8 alpha chain|T-lymphocyte differentiation antigen T8/Leu-2|T8 T-cell antigen |
Swissprots | P01732 B4DT80 Q13970 Q4ZG17 D6W5M8 |
Accessions | AAA59674 AAA79217 AAA79218 AAX88864 EAW99438 EAW99439 EAW99440 EAW99441 P01732 AA668685 AK097942 BAG53555 AK124156 BAC85789 AK300089 BAG61892 AY039664 AAK72403 BC025715 AAH25715 DA075688 DB129686 DQ893323 ABM84249 DQ896638 ABM87637 DQ896639 ABM87638 M12824 AAA61133 M12828 AAB04637 NM_001145873 NP_001139345 NM_001768 NP_001759 NM_171827 NP_741969 NR_027353 |
Function | Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. CD8 alpha chains binds to class I MHC molecules alpha-3 domains. |
Subcellular Location | Isoform 1: Cell membrane; Single-pass type I membrane protein. |
Top Pathways | Hematopoietic cell lineage, T cell receptor signaling pathway, Cell adhesion molecules (CAMs), Primary immunodeficiency, Antigen processing and presentation |
Human CD8 alpha full length protein - ab158045 from Abcam
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Human CD8 alpha protein fragment - ab114161 from Abcam
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Human CD8 peptide - ab101388 from Abcam
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CD8A / CD8 Alpha Antibody Blocking Peptide - LS-E3016 from LifeSpan Bioscience
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CD8A / CD8 Alpha Antibody Blocking Peptide - LS-E3017 from LifeSpan Bioscience
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CD8A / CD8 Alpha Antibody Blocking Peptide - LS-E21621 from LifeSpan Bioscience
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CD8A / CD8 Alpha Antibody Blocking Peptide - LS-E21620 from LifeSpan Bioscience
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Recombinant Human CD8 alpha Protein - H00000925-P01 from Novus Biologicals
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Recombinant Human CD8 alpha Protein - H00000925-Q01 from Novus Biologicals
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Recombinant Human CD8 alpha Protein - H00000925-G01 from Novus Biologicals
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CD8 alpha Peptide - P0378 from Novus Biologicals
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CD8 alpha Peptide - P0377 from Novus Biologicals
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CD8A-Antibody-C-term-Blocking-Peptide - BP1414b from Abgent, a WuXi AppTec company
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CD8A-Antibody-N-term-Blocking-Peptide - BP1414a from Abgent, a WuXi AppTec company
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Human CD8A His tag protein - orb83571 from Biorbyt
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Mouse CD8A His tag protein - orb83544 from Biorbyt
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CD8a protein - orb197686 from Biorbyt
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Ferret CD8A His tag protein - orb84486 from Biorbyt
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CD8 peptide - orb217043 from Biorbyt
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CD8A Blocking Peptide - 33R-3376 from Fitzgerald
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CD8A Blocking Peptide - 33R-7912 from Fitzgerald
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CD8a Blocking Peptide - abx062374 from Abbexa
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Human CD8a Protein - abx065941 from Abbexa
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CD8 - H00000925-G01 from Acris Antibodies
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CD8 - H00000925-P01 from Acris Antibodies
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